Detail of > 4462-55-9
- CAS Number:
- 4462-55-9
- Name:
4-Isoxazolecarbonylchloride, 3-(2,6-dichlorophenyl)-5-methyl-
- Superlist Name:
- 3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carbonyl chloride
- Formula:
- C11H6Cl3NO2
- Molecular Structure:
- Synonyms:
- 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylcarbonylchloride;
- Molecular Weight:
- 290.53
- EINECS:
- 224-723-8
- Density:
- 1.472 g/cm3
- Melting Point:
- 92 °C
- Boiling Point:
- 390.9 °C at 760 mmHg
- Flash Point:
- 190.2 °C
- Appearance:
- Yellow to brown powder
- Hazard Symbols:
C- Risk Codes:
- 34
- Safety:
- 26-36/37/39-45-36/37/39/45Details
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Reference
- Substituted 3-phenyl-5-methylisoxazole-4-carboxanilides with antiinflammatory and analgesic action
- Substituted 3-phenyl-5-methylisoxazole-4-carboxanilides with antiinflammatory and analgesic action. Los Mario, Attilo (Laboratorios Bago S. A., Argent.). Ger. Offen. DE 3247454 A1 28 Jun 1984, 26 pp. (German). (Germany). CODEN: GWXXBX. CLASS: IC: C07D261-18; A61K031-42. APPLICATION: DE 82-3247454 22 Dec 1982. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 1 The title compds. (I; R = H, Cl, F; R1 = H, Me; R2 = Me, Cl, F3C) were prepd. Thus, 3-F3CC6H4NH2 was acylated with 3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarbonyl chloride to give 62% I (R = Cl, R1 = H, R2 = F3C) (II). In the rat paw edema test 50 mg II/kg gave 51.8% redn. in swelling after 1 h and 57.9% redn.Some commonly used reagents like 4462-55-9 is used in this experiment. after 5 h. .
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