Detail of "4511-99-3"

CAS Number:
4511-99-3
Name:
1,2,4-Triazin-3-amine,5,6-diphenyl-
Molecular Structure:
Formula:
C15H12 N4
Molecular Weight:
248.28
Synonyms:
as-Triazine,3-amino-5,6-diphenyl- (6CI,7CI,8CI); 3-Amino-5,6-diphenyl-1,2,4-triazine; NSC58360
Density:
1.229g/cm³
Melting Point:
177 °C
Boiling Point:
463.6°Cat760mmHg
Flash Point:
265.2°C
Hazard Symbols:
Risk Codes:
36/37/38
Safety:
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36/37/39
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Some substituted imidazo[1,2-b][1,2,4]triazines and 8H-pyrimido[1,2-b][1,2,4]triazin-8-ones as potential antineoplastic agents: Some substituted imidazo[1,2-b][1,2,4]triazines and 8H-pyrimido[1,2-b][1,2,4]triazin-8-ones as potential antineoplastic agents. Labouta, Ibrahim M.; Soliman, Farid S. G.; Kassem, Mohamed G. (Fac. Pharm., Univ. Alexandria, Alexandria, Egypt). Pharmazie, 41(11), 812-13 (English) 1986. CODEN: PHARAT. ISSN: 0031-7144. DOCUMENT TYPE: Journal CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 1 Imidazotriazines (I, R1 = Ph, C6H4OMe-4; R2 = Ph; R3 = NO2, Cl) and pyrimidotriazinones (II, R1 = Me, Ph, C6H4OMe-4; R2 = Me, Ph; R3 = Et, CH2Ph, H, BU) were prepd., and some were tested for antitumor activity. Aminoguanidine bicarbonate [2582-30-1] reacted with substituted dicarbonyl compds. to give 3-amino-5,6-disubstituted triazines which reacted with phenacyl bromides, followed by thermal cyclocondensation to give I; whereas the reaction of the aminotriazines with bis(2,4,6-trichlorophenyl) malonates gave II.In this experiment, several chemicals are used like 4511-99-3 None of the tested compds. had significant antitumor activity. .