Reference

Synthetic Applications of 1-Aminoalkyl Chloromethyl Ketones

Synthetic Applications of 1-Aminoalkyl Chloromethyl Ketones. Synthesis of Enantiopure 3-Azetidinols and Aminoalkyl Epoxides. Barluenga, Jose; Baragana, Beatriz; Concellon, Jose M. (Instituto Universitario de Quimica Organometalica Enrique Moles, Universidad de Oviedo, Oviedo 33071, Spain). Journal of Organic Chemistry, 62(17), 5974-5977 (English) 1997 American Chemical Society. CODEN: JOCEAH. ISSN: 0022-3263. DOCUMENT TYPE: Journal CA Section: 27 (Heterocyclic Compounds (One Hetero Atom)) Addn. of several organocerium compds. to chiral 1-aminoalkyl chloromethyl ketones affords, after deprotection, enantiomerically pure 3-azetidinols. The synthesis of enantiopure amino epoxides is also described by successive treatment of chiral a-amino ketones with organocerium compds.Some commonly used reagents like 109-72-8 is used in this experiment. and methyllithium. .