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CAS No.: | 456-59-7 |
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Name: | CYCLANDELATE |
Article Data: | 9 |
Molecular Structure: | |
Formula: | C17H24O3 |
Molecular Weight: | 276.376 |
Synonyms: | Mandelicacid, 3,3,5-trimethylcyclohexyl ester (6CI,7CI,8CI);Cyclohexanol,3,3,5-trimethyl-, mandelate (8CI);3,5,5-Trimethylcyclohexanol, mandelic acidester;Arto-Espasmol;Clandilon;Cyclobral;Natil;Spasmocyclon; |
EINECS: | 207-271-6 |
Density: | 1.085 g/cm3 |
Melting Point: | 55.0-56.5° |
Boiling Point: | 380.1 °C at 760 mmHg |
Flash Point: | 150.1 °C |
Solubility: | Insoluble in water |
PSA: | 46.53000 |
LogP: | 3.47800 |
Product Name: Cyclandelate (CAS NO.456-59-7)
Molecular Formula: C17H24O3
Molecular Weight: 276.37g/mol
Mol File: 456-59-7.mol
Einecs: 207-271-6
Boiling point: 380.1 °C at 760 mmHg
Flash Point: 150.1 °C
Density: 1.08 g/cm3
Surface Tension: 41.8 dyne/cm
Enthalpy of Vaporization: 66.27 kJ/mol
Vapour Pressure: 1.86E-06 mmHg at 25°C
XLogP3-AA: 4.2
H-Bond Donor: 1
H-Bond Acceptor: 3
Product Categories: Cosmetic Ingredients and Chemicals
Cyclandelate (CAS NO.456-59-7) is suitable in the treatment of cerebral arteriosclerosis, brain haggard in traumatic brain injury, venous thrombosis.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD50 | intraperitoneal | 2gm/kg (2000mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 105, Pg. 145, 1956. |
guinea pig | LD50 | intraperitoneal | 2480mg/kg (2480mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 105, Pg. 145, 1956. |
guinea pig | LD50 | oral | 3950mg/kg (3950mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: ATAXIA | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 105, Pg. 145, 1956. |
mouse | LD50 | intraperitoneal | 3780mg/kg (3780mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 105, Pg. 145, 1956. |
mouse | LD50 | oral | > 10gm/kg (10000mg/kg) | Drugs in Japan Vol. 6, Pg. 310, 1982. | |
rat | LD50 | intraperitoneal | 2570mg/kg (2570mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 105, Pg. 145, 1956. |
rat | LD50 | oral | 5gm/kg (5000mg/kg) | Drugs in Japan Vol. 6, Pg. 310, 1982. |
Reported in EPA TSCA Inventory.
Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits acrid smoke and fumes. See also ESTERS.
Cyclandelate ,its CAS NO. is 456-59-7,the synonyms is 3,3,5-Trimethylcyclohexanol alpha-phenyl-alpha-hydroxyacetate ; 3,3,5-Trimethylcyclohexanolalpha-phenyl-alpha-hydroxyacetate ; 3,3,5-Trimethylcyclohexyl hydroxy(phenyl)acetate ; 3,5,5-Trimethylcyclohexanol,mandelicacidester ; 3,5,5-Trimethylcyclohexyl amygdalate ; 3,5,5-Trimethylcyclohexylamygdalate ; 3,5,5-Trimethylcyclohexylmandelate ; Alpha-Hydroxybenzeneacetic acid 3,3,5-trimethylcyclohexyl ester .