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457-87-4

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Basic Information
CAS No.: 457-87-4
Name: (+/-)-N-ETHYLAMPHETAMINE
Article Data: 3
Molecular Structure:
Molecular Structure of 457-87-4 ((+/-)-N-ETHYLAMPHETAMINE)
Formula: C11H17 N
Molecular Weight: 163.263
Synonyms: Phenethylamine,N-ethyl-a-methyl- (6CI,7CI,8CI); (?à)-Ethylamphetamine;2-Ethylamino-1-phenylpropane; Apetinil; Ethylamphetamine; Etilamfetamine;N-Ethyl-a-methylphenethylamine; N-Ethyl-w-phenylisopropylamine;N-Ethylamphetamine
Density: 0.902g/cm3
Boiling Point: 235.3°Cat760mmHg
Flash Point: 95.5°C
Hazard Symbols: F,T
Risk Codes: 11-23/24/25-39/23/24/25
Safety: Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx. See also BENZEDRINE.
PSA: 12.03000
LogP: 2.61800
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Chemistry

Ethylamphetamine(457-87-4)'s molecular formula is C11H17N and its formula weight is 163.26.
The molecular structure of Ethylamphetamine(457-87-4):

History

Ethylamphetamine(457-87-4) was invented in the early 1900s and was subsequently used as an anorectic or appetite suppressant in the 1950s, but was not as commonly used as other amphetamines such as amphetamine, methamphetamine, and benzphetamine, and was largely discontinued once newer drugs such as phenmetrazine were introduced.

Uses

Ethylamphetamine(457-87-4) is used as appetite suppressants or other weight-loss drug, analeptic.

Toxicity Data With Reference

1.   

orl-man TDLo:4286 µg/kg

   THERAP    Therapie. 34 (1979),205.
2.   

orl-rat LD50:250 mg/kg

   BBMS**    Medicaments du Systeme Nerveux Vegetalif Bovet, D., andF. Bovet-Nitti,New York, NY.: S. Karger,1948.
3.   

ipr-rat LDLo:80 mg/kg

   AEPPAE    Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 195 (1940),647.
4.   

ipr-mus LDLo:80 mg/kg

   AEPPAE    Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 195 (1940),647.

Safety Profile

Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx. See also BENZEDRINE.