Reference

On the effect of temperature on the dielectric relaxation time of some benzene derivatives and certain of their binary mixtures

All Rights Reserved. On the effect of temperature on the dielectric relaxation time of some benzene derivatives and certain of their binary mixtures. Vasan, S. T.; Ayachit, Narasimha H.; Deshpande, D. K. (Department of Physics, Rural Engineering College, Hulkoti, India). Physics and Chemistry of Liquids, 44(5), 513-519 (English) 2006 Taylor & Francis Ltd. CODEN: PCLQAC. ISSN: 0031-9104. DOCUMENT TYPE: Journal CA Section: 22 (Physical Organic Chemistry) Dielec. relaxation behavior of polar mols. in a non-polar solvent, or mixts. of these substances at different microwave frequencies and over a range of temps. and concns. give an idea about inter- and intra-mol. forces. Also such studies enable one to calc. thermodn. parameters such as, the change of activation energy for dipole orientation (DG*), the enthalpy (DH*) and entropy (DS*) of activation. Such studies in the case of binary, ternary, etc. mixts. of polar mols. in pure liq. phase or in dil. soln. phase of them in a non-polar solvent help in drawing certain quant. conclusions regarding their relaxation behavior as to whether a single component is responsible for obsd. microwave absorption, or a cooperative phenomenon (av.) by all the dipoles of the mixt. contribute to it. An exptl. investigation is here performed on typical systems. With this in view, systematic dielec.In this experiment, several chemicals are used like 585-79-5 and 459-22-3 measurements in a range of temps. are carried out at a single microwave frequency on a single wt. fraction in benzene of the four substituted phenols, namely, p-fluorophenylacetonitrile, p-bromonitrobenzene, m-bromonitrobenzene and 2-chloro-6-fluorobenzaldehyde and on binary (1:1) mixts. of [2-chloro-6-fluoro-benzaldehyde + o-ethylphenol] and [p-fluorophenylacetonitrile + 2-butylphenol] in benzene as solvent at different temps. The results are presented and discussed. .

4-Arylcyclohexylamines

4-Arylcyclohexylamines. Lednicer, Daniel (Upjohn Co., USA). U.S. US 3979444 7 Sep 1976, 32 pp. (English). (United States of America). CODEN: USXXAM. 38425-26-2 which is the cas registry number is also used here. CLASS: IC: C07C093-18. NCL: 260490000. APPLICATION: US 74-474037 28 May 1974. DOCUMENT TYPE: Patent CA Section: 25 (Noncondensed Aromatic Compounds) Section cross-reference(s): 24, 27, 28 4-Arylcyclohexylamines I [R = Ph, substituted phenyl, 1-naphthyl; R1 = H, OH, OAc; R2 = H or C1-3 alkyl; R3 = H, C1-3 alkyl, or (CH2)3COR4 (R4 = Ph or substituted phenyl); or R2R3N = pyrrolidino, piperidino, morpholino, etc.] and their salts, which depress the central nervous system and lower the blood pressure, were prepd. by procedures involving up to 13 steps. Thus, PhCH2CN added to CH2:CHCO2Me to give NCCPh(CH2CH2CO2Me)2, which was cyclized and decarboxylated to 4-oxo-1-phenylcyclohexanecarbonitrile, the oxo group then protected and the CN group successively hydrolyzed, reduced, and acetylated; the oxo group was then reduced to OH, mesylated, reacted with NaN3 and reduced to convert the mesyloxy group to NH2 (and the AcO group to OH), after which cyclization with Br(CH2)4Br gave I (R = Ph, R1 = OH, R2R3N = pyrrolidino). .