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Detail of "465-21-4"

  • MSDS Download
  • CAS Number:
  • 465-21-4
  • Name:
  • Bufalin

  • Molecular Structure:
  • Formula:
  • C24H34O4
  • Molecular Weight:
  • 386.52
  • Synonyms:
  • 5b-Bufa-20,22-dienolide, 3b,14-dihydroxy- (7CI,8CI);5β-Bufa-20,22-dienolide, 3β,14-dihydroxy-;NSC 89595;Bufa-20,22-dienolide, 3,14-dihydroxy-, (3β,5β)-;3-beta,14-Dihydroxy-5-beta-bufa-20,22-dienolide;3,14-Dihydroxy-bufa-20,22-dienolide;
  • Density:
  • 1.226 g/cm3
  • Boiling Point:
  • 556.6 °C at 760 mmHg
  • Flash Point:
  • 189 °C
  • Hazard Symbols:
  • VeryT+
  • Risk Codes:
  • 28
  • Safety:
  • 28-36/37-45 Details
  • Transport Information:
  • UN 3462 6.1/PG 2

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CAS No.465-21-4 BufalinCompetitive Product

Assay:98%  Appearance:powder  Package:20mg;100mg;5...

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CAS No.465-21-4 Bufalin

Assay:≥98%HPLC  Package:20mg;50mg;10...Storage:Store in dry...  Application:Analytical S...

Bufalin

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CAS No.465-21-4 Bufalin

Assay:97%  Appearance:powder or cr...  Package:10mg,20mg,1g...Storage:-20degree

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CAS No.465-21-4 Bufalin

Quick Details Type: Herbal Extract Variety: Other Form: Powder Part: Shell Extraction Type: Other Packaging: Drum Place of Origin: China (Mainland) Grade: First grade White powder: White powder Model Number: 98% CAS NO:465-21-4 Packaging & Delivery Packaging Detai

Supplier:Shenyang Meiyao Chemical Co., Ltd., [ China (Mainland)]

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CAS No.465-21-4 Bufalin

Supplier:WBV International Limited. [ China (Mainland)]

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CAS No.465-21-4 Bufalin

Supplier:Hangzhou Dayangchem Co., Ltd. [ China (Mainland)]

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CAS No.465-21-4 Bufalin

TOXICITY: SAFETY: Production: Others: Bufalin 465-21-4 >98% HPLC Cinobufagin 470-37-1 >98% HPLC Astilbin 29838-67-3 >99% HPLC Engelitin >99% HPLC Polyphyllin Ⅰ 50773-41-6 >98% HPLC Polyphyllin Ⅱ >98% HPLC

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CAS No.465-21-4 Bufalin

Product name:Bufalin CAS No:465-21-4 Purity:98%by HPLC Molecular formular:C24H34O4 Molecular weight:386.52 Appearance:white powder Packing:20mg,100mg,1g Storage:Store at 2-8 degree, keep dry and dark

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CAS No.465-21-4 Bufalin

English name:Bufalin CAS:465-21-4 Purity:HPLC>98% Detail Information: Molecular Formula : C24H34O4 Molecular Weight : 368.5 Original:Venenum Bufonis Synonyms:3-BETA-14-DIHYDROXY-5-BETA-BUFA-20,22-DIENOLIDE Package: 20mg; 100mg;1g Storage:-4-2°C, store in

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CAS No.465-21-4 Bufalin

Product name:Bufalin CAS: 465-21-4 Molecular formula: C24H34O4 Molecular mass:386.52

Supplier:Chengdu Herbpurify Co., Ltd [ China (Mainland)]

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465-21-4Bufalin >98% HPLC

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Bufalin

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CAS No.465-21-4 Bufalin

>98%(HPLC)

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Bufalin HPLC≥98%

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[Name]Bufalin [Assay]+98% [CasNo]465-21-4 [Pack]100mg.1g .10g [Contact email] herbest3@gmail.com

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Reference

Studies on the quality estimation of drugs of animal origins
Studies on the quality estimation of drugs of animal origins. I. The determination of bufadienolides in Ch' an Su (Senso) and its preparations. Kubo, Kiichi; Takakuwa, Tokutaro; Handa, Kazuyoshi (Kokando Co., Ltd., Toyama, Japan). Yakugaku Zasshi, 97(3), 274-81 (Japanese) 1977. CODEN: YKKZAJ. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) The quality estn. of Ch' an Su Senso, based on the chromatog. detn. of three major bufadienolides (resibufogenin [465-39-4], cinobufagin [470-37-1], and bufalin [465-21-4]) was investigated. Reliable methods established by the use of gas-liquid chromatog., high performance-liquid chromatog., and thin-layer densitometry were found to be routinely applicable for bufadienolide detn. of Rokushingan, a commercial drug contg. Ch' an Su.
Cardiotonic activities of some new type of bufadienolide- and cardenolide-conjugates
Cardiotonic activities of some new type of bufadienolide- and cardenolide-conjugates. Shigei, T.; Tsuru, H.; Ishikawa, N. (Sch. Med., Nagoya Univ., Nagoya, Japan). Experientia, 33(2), 258-60 (English) 1977. CODEN: EXPEAM. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Using digitoxigenin as a standard (1.0), the cardiotonic activity of bufodienolide- and cardenolide-conjugates in isolated hypodynamic frog and guinea pig hearts was detd. In the frog heart bufalin [465-21-4] and bufalin 3-sulfate [54603-10-0] had relative potencies of 0.3 and 1.0, resp. Gamabufotalitoxin [53915-36-9] and related compds. ranged from 0.3-1.0. The range for seven of the 8 digitoxigenin 3-suberoyl amino acid esters was 0.1-1.0. Digitoxigenin 3-suberoyl L-proline ester [38676-77-6] had a value of 0.03. In the guinea pig heart the potencies of bufalin and the gramabufotalitoxins were considerably higher, 10.0 and 1.3-3.0, resp. Thus, the frog heart is less sensitive to bufadienolides, but not cardenolides, than the mammalian heart.
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