CAS No.465-39-4,Resibufogenin Suppliers

Products Categories

Pharmaceutical (37)
Plant Extract (23)
Organic Chemicals (9)
Others (8)
Reagent (3)
Materials (1)

Basic Information

Molecular Structure:
CAS No.:	465-39-4
Name:	Resibufogenin
Article Data:	5

Formula:	C₂₄H₃₂O₄
Molecular Weight:	384.516
Synonyms:	5b-Bufa-20,22-dienolide, 14,15b-epoxy-3b-hydroxy- (6CI,7CI,8CI);14,15b-Epoxy-3b-hydroxy-5b-bufa-20,22-dienolide;3b-Hydroxy-14,15b-epoxy-5b-bufa-20,22-dienolide;Bufogenin;NSC 90783;Recibufogenin;Resi;Resibufogenin;Respigon;
Density:	1.25 g/cm³
Melting Point:	155oC
Boiling Point:	554.9 °C at 760 mmHg
Flash Point:	190.7 °C
Solubility:	Soluble in chloroform.
Appearance:	White to off-white solid.
Safety:	24/25
PSA:	62.97000
LogP:	4.25830

Total:71 Page 1 of 2 1 2 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 465-39-4

Specification

The Bufogenin, with the CAS registry number 465-39-4, is also known as 14,15β-Epoxy-3β-hydroxy-5β-bufa-20,22-dienolide. It belongs to the product category of Steroids. This chemical's molecular formula is C₂₄H₃₂O₄ and molecular weight is 384.51. What's more, its systematic name is called (3β,5β,15β)-3-Hydroxy-14,15-epoxybufa-20,22-dienolide. It need to store in a cool dark place.

Physical properties about Bufogenin are: (1)ACD/LogP: 2.90; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.9; (4)ACD/LogD (pH 7.4): 2.9; (5)ACD/BCF (pH 5.5): 93.39; (6)ACD/BCF (pH 7.4): 93.39; (7)ACD/KOC (pH 5.5): 895.28; (8)ACD/KOC (pH 7.4): 895.28; (9)#H bond acceptors: 4; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 48.06 Å²; (13)Index of Refraction: 1.602; (14)Molar Refractivity: 105.54 cm³; (15)Molar Volume: 307.4 cm³; (16)Surface Tension: 52 dyne/cm; (17)Density: 1.25 g/cm³; (18)Flash Point: 190.7 °C; (19)Enthalpy of Vaporization: 96.09 kJ/mol; (20)Boiling Point: 554.9 °C at 760 mmHg; (21)Vapour Pressure: 1.26E-14 mmHg at 25 °C.

You can still convert the following datas into molecular structure:
(1) SMILES: O=C\1O\C=C(/C=C/1)[C@@H]4[C@@]6(C)CC[C@H]3[C@@H](CC[C@@H]2C[C@@H](O)CC[C@@]23C)[C@]65O[C@@H]5C4
(2) InChI: InChI=1S/C24H32O4/c1-22-9-7-16(25)11-15(22)4-5-18-17(22)8-10-23(2)19(12-20-24(18,23)28-20)14-3-6-21(26)27-13-14/h3,6,13,15-20,25H,4-5,7-12H2,1-2H3/t15-,16+,17+,18-,19-,20-,22+,23-,24-/m1/s1
(3) InChIKey: ATLJNLYIJOCWJE-CWMZOUAVSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
frog	LD50	parenteral	7830ug/kg (7.83mg/kg)	Drugs of the Future. Vol. 12, Pg. 837, 1987.
mouse	LD50	intraperitoneal	14mg/kg (14mg/kg)	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 1239, 1982.
mouse	LD50	intravenous	4250ug/kg (4.25mg/kg)	Drugs in Japan Vol. 6, Pg. 899, 1982.
mouse	LD50	oral	59800mg/kg (59800mg/kg)	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 1239, 1982.
mouse	LD50	subcutaneous	104mg/kg (104mg/kg)	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 24, Pg. 1239, 1982.
rat	LD50	intravenous	2200ug/kg (2.2mg/kg)	Drugs in Japan Vol. 6, Pg. 899, 1982.
rat	LD50	parenteral	21mg/kg (21mg/kg)	Drugs of the Future. Vol. 12, Pg. 837, 1987.