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Detail of "475-83-2"

  • CAS Number:
  • 475-83-2
  • Name:

  • 4H-Dibenzo[de,g]quinoline,5,6,6a,7-tetrahydro-1,2-dimethoxy-6-methyl-, (6aR)-

  • Superlist Name:
  • Nuciferine
  • Molecular Structure:
  • Formula:
  • C19H21NO2
  • Molecular Weight:
  • 295.38
  • Synonyms:
  • 4H-Dibenzo[de,g]quinoline,5,6,6a,7-tetrahydro-1,2-dimethoxy-6-methyl-, (R)-;6ab-Aporphine, 1,2-dimethoxy- (8CI);Nuciferine (6CI,7CI);(-)-Nuciferine;(R)-1,2-Dimethoxyaporphine;(R)-Nuciferine;1,2-Dimethoxy-6ab-aporphine;D-(-)-Nuciferine;Nuciferin;Sanjoinine E;l-Nuciferine;
  • Density:
  • 1.15 g/cm3
  • Boiling Point:
  • 430.7 °C at 760 mmHg
  • Flash Point:
  • 151.9 °C
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CAS No.475-83-2 NuciferineCompetitive Product

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Name:4H-Dibenzo[de,g]quinoline,5,6,6a,7-tetrahydro-1,2-dimethoxy-6-methyl-, (6aR)-

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Nuciferine Molecular Formula ：C19H21NO2 Molecular Weight ：295.38

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Nuciferine(C19H21NO2) Latin name:Nelumbo nucifera gaertn Part used: Leaf Active ingredient: Nuciferine 2%and Flavonoids 20%30% by UV Cas No 475-83-2 Molecular Formula:C19H21NO2 Molecular Weight:295.376 Appearance:Brown powder Microbiological Total plate count

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Reference

Dimethoxyaporphine as an antagonist of chemical excitation in the pigeon optic tectum
Dimethoxyaporphine as an antagonist of chemical excitation in the pigeon optic tectum. Felix, Dominik; Frangi, Ursula (Brain Res. Inst., Univ. Zurich, Zurich, Switz.). Neurosci. Lett., 4(6), 347-50 (English) 1977. CODEN: NELED5. DOCUMENT TYPE: Journal CA Section: 3 (Biochemical Interactions) Section cross-reference(s): 2 L-nuciferine (L-5,6-dimethoxyapomorphine)(I) [475-83-2] antagonized the excitatory activities of L-glutamate [56-86-0] and, to a lesser extent, of L-aspartate [56-84-8] and DL-homocysteate [504-33-6] on nerves of the pigeon optic tectum. The rapid effect of I suggests a direct physicochem. action on the postsynaptic membrane rather than any interference with cellular metab. I did not affect the excitation produced by acetylcholine, suggesting its use as a specific tool for investigating amino acid neurotransmitters.
The specificity of action of three possible antagonists of amino acid-induced neuronal excitations
The specificity of action of three possible antagonists of amino acid-induced neuronal excitations. McLennan, H.; Wheal, H. V. (Dep. Physiol., Univ. Br. Columbia, Vancouver, B. C., Can.). Neuropharmacology, 15(11), 709-12 (English) 1976. CODEN: NEPHBW. DOCUMENT TYPE: Journal CA Section: 2 (Hormone Pharmacology) Electrophoretically applied glutamic acid di-Et ester [16450-41-2] antagonized the effects of Na glutamate and Na aspartate in a single thalamic rat neuron to a greater extent than those of Na DL-homocysteate or acetylcholine bromide. 1-Hydroxy-3-amino-2-pyrrolidone [1003-51-6] distinguished between glutamate/aspartate and homocysteate but not acetylcholine. Nuciferine [475-83-2] showed no selectivity amongst the amino acids. However, large applications of any of the antagonists antagonized the effects of all of the excitatory agonists.
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