Detail of "47689-67-8"

CAS Number:
47689-67-8
Name:
L-Tyrosine,O-[[(2-bromophenyl)methoxy]carbonyl]-N-[(1,1-dimethylethoxy)carbonyl]-
Superlist Name:
Boc-O-(2-bromo-Cbz)-L-Tyrosine
Molecular Structure:
Formula:
C₂₂H₂₄BrNO₇
Molecular Weight:
494.33
Deleted CAS:
205442-81-5|54784-65-5
Synonyms:
L-Tyrosine,N-[(1,1-dimethylethoxy)carbonyl]-, (2-bromophenyl)methyl carbonate (ester)(9CI);N-(tert-Butoxycarbonyl)-O-(2-bromobenzyloxycarbonyl)-L-tyrosine;O-{[(2-bromobenzyl)oxy]carbonyl}-N-(tert-butoxycarbonyl)-D-tyrosine;(2R)-3-[4-[(2-bromophenyl)methoxycarbonyloxy]phenyl]-2-[(2-methylpropan-;
Density:
1.414 g/cm³
Melting Point:
112-115 °C
Boiling Point:
634.9 °C at 760 mmHg
Flash Point:
337.8 °C

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Reference

Preparation of peptide that inhibits blood triglyceride level rise and blood triglyceride level rise inhibitor containing this peptide as active ingredient: Preparation of peptide that inhibits blood triglyceride level rise and blood triglyceride level rise inhibitor containing this peptide as active ingredient. Kagawa, Kyoichi; Fukuhama, Chizuko; Matsutaka, Hisako; Nakamura, Toyoo; Numata, Masahiro; Watanabe, Shigeaki; Honda, Kazuhisa ( Hankyu-Kyoei Bussan Co., Ltd.; Itoham Foods Inc.; Kagawa, Kyoichi; Fukuhama, Chizuko; Matsutaka, Hisako; Nakamura, Toyoo; Numata, Masahiro; Watanabe, Shigeaki; Honda, Kazuhisa, Japan). PCT Int. Appl. WO 9700890 A1 9 Jan 1997, 26 pp. DESIGNATED STATES: W: AU, CA, FI, KR, NO, US; RW: AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE. (Japanese). (World Intellectual Property Organization). CODEN: PIXXD2. CLASS: ICM: C07K007-06. ICS: A23K001-16; A23L001-305; A61K038-08; A61K038-06. APPLICATION: WO 1995-JP1264 23 Jun 1995. DOCUMENT TYPE: Patent CA Section: 34 (Amino Acids, Peptides, and Proteins) Section cross-reference(s): 1, 17 A peptide having an amino acid sequence as specified in the sequence H-Leu-Val-Val-Tyr-Pro-Trp-Thr-OH (I), H-Val-Tyr-Pro-OH (II) and/or H-Val-Thr-Leu-OH (III) is prepd. by hydrolysis of globin by acidic protease of Aspergillus niger at 50° for 3 h and HPLC purifn. 13139-14-5 which is the cas registry number is also used here. and also prepd. by the solid phase synthesis. A blood triglyceride level rise inhibitor contg. above peptide(s) as the active ingredient and a feed and a specified health food contg. the above peptide(s) as the active ingredient and having the function of inhibiting blood triglyceride level rise are claimed. The invention enables prevention or treatment of human or animal obesity, hyperlipemia and accompanying circulatory diseases such as hypertension and arteriosclerosis, and improvements in the meat quality of livestock and culture fish. Thus, I was prepd. using a SAM2 peptide synthesizer (Biosearch) by sequential coupling of N-Boc-protected amino acids on a Boc-Thr(Bzl)-resin, resin-cleavage and deprotection with HF(l) contg. anisole, and purifn. on an octadecyl silica column. I, II, and III at 5.6′10-4, 0.34, and 0.43 mg/mouse in vivo inhibited 50% blood triglyceride level rise in mice fed with 250 mg olive oil. .

Detail of "47689-67-8"

L-Tyrosine,O-[[(2-bromophenyl)methoxy]carbonyl]-N-[(1,1-dimethylethoxy)carbonyl]-

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CAS No.47689-67-8 Boc-O-(2-bromo-Cbz)-L-Tyrosine

CAS No.47689-67-8 Boc-O-(2-bromo-Cbz)-L-Tyrosine

CAS No.47689-67-8 Boc-O-(2-bromo-Cbz)-L-Tyrosine

CAS No.47689-67-8 Boc-O-(2-bromo-Cbz)-L-Tyrosine

CAS No.47689-67-8 Boc-O-(2-bromo-Cbz)-L-Tyrosine

CAS No.47689-67-8 Boc-O-(2-bromo-Cbz)-L-Tyrosine

CAS No.47689-67-8 Boc-O-(2-bromo-Cbz)-L-Tyrosine

CAS No.47689-67-8 Boc-O-(2-bromo-Cbz)-L-Tyrosine

CAS No.47689-67-8 Boc-O-(2-bromo-Cbz)-L-Tyrosine

CAS No.47689-67-8 Boc-O-(2-bromo-Cbz)-L-Tyrosine

CAS No.47689-67-8 Boc-O-(2-bromo-Cbz)-L-Tyrosine

CAS No.47689-67-8 Boc-O-(2-bromo-Cbz)-L-Tyrosine

CAS No.47689-67-8 Boc-O-(2-bromo-Cbz)-L-Tyrosine

CAS No.47689-67-8 Boc-O-(2-bromo-Cbz)-L-Tyrosine

CAS No.47689-67-8 Boc-O-(2-bromo-Cbz)-L-Tyrosine

CAS No.47689-67-8 Boc-O-(2-bromo-Cbz)-L-Tyrosine

CAS No.47689-67-8 Boc-O-(2-bromo-Cbz)-L-Tyrosine

CAS No.47689-67-8 Boc-O-(2-bromo-Cbz)-L-Tyrosine

CAS No.47689-67-8 Boc-O-(2-bromo-Cbz)-L-Tyrosine

CAS No.47689-67-8 Boc-O-(2-bromo-Cbz)-L-Tyrosine

Reference