Detail of "47822-79-7"

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Photoelectrochemical characteristics and behavior of a surfactant aluminum phthalocyanine cell

Photoelectrochemical characteristics and behavior of a surfactant aluminum phthalocyanine cell. Belanger, D.; Dodelet, J. P.; Dao, L. H.; Lombos, B. A. (INRS-Energie, Varennes, PQ J0L 2P0, Can.). J. Phys. Chem., 88(19), 4288-95 (English) 1984. CODEN: JPCHAX. ISSN: 0022-3654. DOCUMENT TYPE: Journal CA Section: 52 (Electrochemical, Radiational, and Thermal Energy Technology) Solid-liq. junction cells were prepd. by joining the surfactant Al phthalocyanine (AlPc) [47822-79-7] with various redox systems. AlPc was electrodeposited on Nesa glass (an In-Sn oxide-coated transparent glass), Sb-doped SnO2 of 2 resistivities, and on Au electrodes. Good quality org. films were obtained for thicknesses of 270-4000 ?. Concn. and pH conditions were optimized for the best redox systems: Fe(CN)63-/4-, HQ, and I3-/I-. Fe3+/2+, Sn4+/2+, and Fe(EDTA)1-/2- were also used but were not optimized. I penetration into the film revealed 2 kinds of AlPc aggregates having action spectra with different band intensities in the red. A weak charge-transfer complex between AlPc and Q is also postulated, causing the pigment flat-band potential to shift with pH. O adsorbed on the pigment is a mediator for the photoelectron transfer to Fe(CN)63-. No O effect was found for Q or I3-. The max. exciton diffusion length in AlPc is 250 ?. The max. quantum efficiency is 4% at 630 nm and 0.26 mW/cm2 and the power efficiency is ~10-2% under white light irradn. at 0.5-100 mW/cm2. These values were obtained with Q/HQ at pH 2.5 where concn. of Q = concn. of HQ = 7.5 ′ 10-3M for an ~1000-?-thick cell. A max. open-circuit voltage of 0.15 V is theor. expected with Q/HQ. Exptl., the max. value obtained at white light illumination of 100 mW/cm2 was 0.13 V. Short-circuit current increases as the sheet resistivity of the Ohmic electrode decreases, showing the importance of the Ohmic contact in the series resistance of the cell. The fill factor in all cases was 0.25.

Photocytotoxic efficacy of sulfonated species of aluminum phthalocyanine against cell monolayers, multicellular spheroids and in vivo tumors

Photocytotoxic efficacy of sulfonated species of aluminum phthalocyanine against cell monolayers, multicellular spheroids and in vivo tumors. Chan, W. S.; West, C. M. L.; Moore, J. V.; Hart, I. R. (Biol. Metastasis Lab., Imp. Cancer Research Fund, London WC2A 3PX, UK). Br. J. Cancer, 64(5), 827-32 (English) 1991. CODEN: BJCAAI. ISSN: 0007-0920. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Section cross-reference(s): 8 The uptake and ability to mediate photocytotoxicity of mono-, di-, tri-, and tetra-sulfonated derivs. of chloroaluminum phthalocyanin (AlS1-4Pc) were studied in monolayer cultures of murine Colo 26 cells and in monolayer and spheroid cultures of human WiDr cells. Cells treated in vitro in monolayers or spheroids with the less sulfonated derivs. AlS1Pc and AlS2Pc were more susceptible to photocytotoxicity than those treated with AlS3Pc cells treated with AlS4Pc were even less susceptible to the cytotoxic effects of light irradn. These results mirrored the cellular uptake in vitro. When WiDr spheroids were increased in size from 250 to 500 mm, there was a redn. in the uptake of AlS1Pc and AlS2Pc which was reflected by the decreased sensitivity of the larger spheroids to the effects of light irradn. AlS1Pc had no effect against Colo 26 cells growing as s.c. tumors in syngeneic BALB/c mice. AlS3Pc, AlS2-Pc, and AlS4Pc reduced tumor wts. 5 days after laser light irradn. 47822-79-7 and 68508-15-6 which are cas registry numbers of substances are two of reagents here. AlS2Pc had the most dramatic effect on the colony-forming efficiency of tumor cells recovered 24 h after photodynamic therapy. Despite the effects on tumor size, AlS3Pc and AlS4Pc scarcely affected the subsequent viability of cells from dissocd. tumors. Thus, the in vitro efficacy of the sulfonated derivs. of phthalocyanin is not necessarily predictive of their in vivo effectiveness. .