Detail of "479-43-6"

Reference

HPLC analysis of alkaloids in Ku Mu [Picrasma quassioides (D

HPLC analysis of alkaloids in Ku Mu [Picrasma quassioides (D. Don. Benn.)]. Luo, Wenyu; Zhang, Yuzhong (Inst. Chin. Mater. Med., Acad. Tradit. Chin. Med., Peop. Rep. China). Yaowu Fenxi Zazhi, 5(1), 11-14 (Chinese) 1985. CODEN: YFZADL. ISSN: 0254-1793. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) 1-Carbomethoxy-b-carboline (I) [3464-66-2], 1-carboethoxy-b-carboline (II) [72755-19-2], 1-vinyl-4,8-dimethoxy-b-carboline (III) [65236-62-6], canthin-6-one (IV) [479-43-6] and 4,5-dimethoxy-b-canthin-6-one (V) [18110-87-7] in the stem of P. quassiuoides were detd. by HPLC. Thus, ~0.1-g powder was extd. with 25 mL MeOH, and the ext. was subjected to anal. by HPLC with a column contg. Nucleosil C18 as stationary phase [MeOH-NH4OAc (.1) as mobile phase]. The peak height was linearly related to concns. of 0.1-1.0 mg. Reproducibility with a relative std. deviation of 1.75-3.24% was obsd. Alkaloid concns. in the stem were 0.067, 0.011, 0.008, 0.096 and 0.012%, resp.

Correlation between phylogeny, chemical constituents and pharmaceutical aspects of plants and their applications in drug research

Correlation between phylogeny, chemical constituents and pharmaceutical aspects of plants and their applications in drug research. (Chinese Academy of Medical Sciences; Lab. Med. Plants, Inst. Materia Med., Peop. R. China). Chih Wu Hsueh Pao, 19(4), 257-62 (Chinese) 1977. CODEN: CHWHAY. ISSN: 0577-7496. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 11 Pharmacol. properties, chem. constituents and phylogeny of Picrasma quassioides, Zanthoxylum elephantiasis, Berberis poiretii, Stephania and 33 Rhododendron species were investigated. P. quassioides contains antibacterial nigakinone [18110-86-6] and methylnigakinone [18110-87-7], and Z. elephantiasis contained antibacterial canthin-6-one [479-43-6]. B. poirettii roots contained coptisine [3486-66-6], an antimicrobial agent previously found in Coptis roots. Cepharanthine [481-49-2] isolated from Stephania showed leukocyte-increasing activity. Farrerol [24211-30-1], astragalin [480-10-4], kaempferol [520-18-3], and scopoletin [92-61-5] from Rhododendron had expectorant activity, and hyperin [482-36-0] and quercetin [117-39-5] from Rhododendron are antitussives.