Reference

Chemical studies on Cirsium species (V)

Chemical studies on Cirsium species (V). Chemical constituents of the roots of Cirsium xanthocanthum. Lee, Yong Choo; Park, Young Hoon (Coll. Pharm., Sung Kyun Kwan Univ., Suweon 170, S. Korea). Saengyak Hakhoe Chi (Hanguk Saengyak Hakhoe), 15(2), 74-7 (Korean) 1984. CODEN: SYHJAM. ISSN: 0253-3073. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 11 Linarin (I) [480-36-4] was isolated from C. xanthocanthum roots used for treatment of arthritis, neuralgia and carbuncular abscess.

A gradient HPLC method for the quality control of chlorogenic acid, linarin and luteolin in Flos Chrysanthemi Indici suppository

All Rights Reserved. A gradient HPLC method for the quality control of chlorogenic acid, linarin and luteolin in Flos Chrysanthemi Indici suppository. Zhang, Qunlin; Li, Jun; Wang, Chao; Sun, Wei; Zhang, Zhongtang; Cheng, Wenming (School of Pharmacy, Anhui Medical University, Anhui 230032, Peop. Rep. China). Journal of Pharmaceutical and Biomedical Analysis, 43(2), 753-757 (English) 2007 Elsevier B.V. CODEN: JPBADA. ISSN: 0731-7085. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) The Flos Chrysanthemi Indici suppository, a famous traditional Chinese medicine, is marketed for the treatment of prostatitis and chronic pelvic inflammation. A simple, relatively rapid and accurate high-performance liq. chromatog. (HPLC) method was applied to the simultaneous detn.There are some reagents with their cas registry numbers 491-70-3 and 480-36-4 are used in this study. of chlorogenic acid, linarin and luteolin in Flos Chrysanthemi Indici suppository. The good sepn. was achieved on a Hypersil ODS column by a gradient elution using the mixt. of acetonitrile and aq. 1.0% acetic acid as mobile phase within 23 min. The method was validated for 3 active phenolic compds. with the relative std. deviations (R.S.D.) of intra- and inter-day precision below 3.0%, and the detection limits (S/N = 3) of chlorogenic acid, linarin and luteolin were 0.32, 0.08 and 0.05 mg ml-1, resp. This assay was successfully applied to the detn. of 3 active phenolic compds. in Flos Chrysanthemi Indici suppository samples with the quant. recoveries in the range of 94.7-101.8%. The results indicate that the developed HPLC method can be readily utilized as a quality control method for Flos Chrysanthemi Indici suppository and its related traditional Chinese medicinal prepns. .