Detail of "4812-45-7"
- CAS Number:
- 4812-45-7
- Name:
1H-Indazole,3-chloro-5-nitro-
- Molecular Structure:
- Formula:
- C7H4ClN3O2
- Molecular Weight:
- 197.58
- Synonyms:
- 3-Chloro-5-nitro-1H-indazole;3-Chloro-5-nitroindazole;3-Chloro-5-nitro-1H-indazole ,97%;
- EINECS:
- 225-380-7
- Density:
- 1.661g/cm3
- Melting Point:
- 218-220 °C
- Boiling Point:
- 234.7 °C at 760 mmHg
- Flash Point:
- 95.7 °C
- Hazard Symbols:
Xi
1H-Indazole,3-chloro-5-nitro-
Xi
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Reference
- Experimental study of the parasiticidal properties of indazole: fungi
- Experimental study of the parasiticidal properties of indazole: fungi. Bailenger, J. (Lab. Org. Anim. Parasitol. Mycol. Hum., UER Pharm., Bordeaux F 33076, Fr.). Ann. Pharm. Fr., 42(4), 379-85 (French) 1984. CODEN: APFRAD. ISSN: 0003-4509. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Section cross-reference(s): 10 3-Chloro-5-nitroindazole (I) [4812-45-7] and 3-chloro-6-nitroindazole (II) [50593-68-5] had min. inhibitory concns. (MIC) of 13.3-40 mg/mL against most of the fungi tested, while the MIC's of the corresponding 1-acetyl derivs. were 100-500 mg/mL. When tested in mice with Candida infestation of the digestive tract, I, at a daily dose of 300 mg/kg, was not effective in curing the animals, but did prevent further proliferation of the fungus.