Reference

Taurine conjugates as metabolites of arylacetic acids in the ferret

Taurine conjugates as metabolites of arylacetic acids in the ferret. Idle, Jeffrey R.; Millburn, Peter; Williams, R. Tecwyn (Med. Sch., St. Mary's Hosp., London, Engl.). Xenobiotica, 8(4), 253-64 (English) 1978. 103-82-2 is just another one chemical used in this study. CODEN: XENOBH. ISSN: 0049-8254. DOCUMENT TYPE: Journal CA Section: 3 (Biochemical Interactions) Phenylacetic acid (I) [103-82-2], 4-chlorophenylacetic acid (II) [1878-66-6], 4-nitrophenylacetic acid (III) [104-03-0], a-methylphenylacetic acid (IV) [492-37-5], 1-naphthylacetic acid (V) [86-87-3], 2-naphthylacetic acid (VI) [581-96-4], and indol-3-ylacetic acid (VII) [87-51-4] administered to ferrets were excreted in the urine as taurine and glycine conjugates. Diphenylacetic acid [117-34-0] did not form an amino acid conjugate and was excreted as a glucuronide. The taurine conjugate was the major metabolite of III, IV, V, VI, and VII whereas the glycine conjugate was the major metabolite of I and II. Taurine conjugation did not occur with benzoic acid [65-85-0] and 4-nitrobenzoic acid [62-23-7], which were excreted as glycine and glucuronic acid conjugates. The role of taurine as an alternative to glycine in the metabolic conjugation of arylacetic acids is discussed. .

Deno's oxidation - analysis of oxidation products from model compounds

Deno's oxidation - analysis of oxidation products from model compounds. Dumay, Dominique; Kirsch, Gilbert; Gruber, Rene; Cagniant, Denise (Lab. Carbochim. Synth. Org., Univ. Metz, Metz 57045, Fr.). Fuel, 63(11), 1544-6 (English) 1984. CODEN: FUELAC. ISSN: 0016-2361. DOCUMENT TYPE: Journal CA Section: 51 (Fossil Fuels, Derivatives, and Related Products) Oxidns. by CF3COOH-H2O2-H2SO4 systems were used for the possible detn. of coal structure. Before applying the method to study heavy residues from coal liquefaction, the procedure was applied to 1,2-diphenylethane [103-29-7], a-phenylpropionic acid [492-37-5], diacids, and long-chain fatty acids. The acids were chosen because they are expected products from coal oxidn. The oxidn. products obtained were analyzed by gas chromatog. or combined gas chromatog.-mass spectroscopy. This oxidn. method could thus not be easily applied to detn. of coal structure.