492-41-1

Reported in EPA TSCA Inventory.

The L-(-)-Ephedrine is an organic compound with the formula C₉H₁₃NO. The IUPAC name of this chemical is (1R,2S)-2-amino-1-phenylpropan-1-ol. With the CAS registry number 492-41-1, it is also named as (-)-erythro-2-Amino-2-methyl-1-phenylethanol. The product's classification codes are Drug / Therapeutic Agent; Human Data. Besides, it is a white powder, which should be stored in dry and well-ventilated place at temperature of 2 - 8 °C.

Physical properties about L-(-)-Ephedrine are: (1)ACD/LogP: 0.81; (2)ACD/LogD (pH 5.5): -2.21; (3)ACD/LogD (pH 7.4): -1.07; (4)ACD/BCF (pH 5.5): 1; (5)ACD/BCF (pH 7.4): 1; (6)ACD/KOC (pH 5.5): 1; (7)ACD/KOC (pH 7.4): 1; (8)#H bond acceptors: 2; (9)#H bond donors: 3; (10)#Freely Rotating Bonds: 4; (11)Polar Surface Area: 12.47 Å²; (12)Index of Refraction: 1.557; (13)Molar Refractivity: 45.46 cm³; (14)Molar Volume: 141 cm³; (15)Polarizability: 18.02×10^-24cm³; (16)Surface Tension: 45 dyne/cm; (17)Density: 1.071 g/cm³; (18)Flash Point: 128.1 °C; (19)Enthalpy of Vaporization: 55.7 kJ/mol; (20)Boiling Point: 288.1 °C at 760 mmHg; (21)Vapour Pressure: 0.0011 mmHg at 25°C.

Uses of L-(-)-Ephedrine: it can be used to produce (4R,5S)-(+)-4-methyl-5-phenyloxazolidin-2-one by heating. It will need reagent potassium carbonate and solvent toluene with reaction temperature of 130 °C. The yield is about 80%.

When you are using this chemical, please be cautious about it as the following:
It is harmful if swallowed. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Besides, this chemical is irritating to eyes, respiratory system and skin. When you are using it, wear suitable gloves and eye/face protection.

You can still convert the following datas into molecular structure:
(1)SMILES: O[C@H](c1ccccc1)[C@@H](N)C
(2)InChI: InChI=1/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3/t7-,9-/m0/s1
(3)InChIKey: DLNKOYKMWOXYQA-CBAPKCEABA
(4)Std. InChI: InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3/t7-,9-/m0/s1
(5)Std. InChIKey: DLNKOYKMWOXYQA-CBAPKCEASA-N

The toxicity data is as follows: