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494-38-2

Basic Information
CAS No.: 494-38-2
Name: ACRIDINE ORANGE
Article Data: 11
Molecular Structure:
Molecular Structure of 494-38-2 (ACRIDINE ORANGE)
Formula: C17H19 N3
Molecular Weight: 265.358
Synonyms: 3,6-Acridinediamine,N,N,N',N'-tetramethyl- (9CI); Acridine, 3,6-bis(dimethylamino)- (6CI,8CI);3,6-Bis(dimethylamino)acridine; 3,6-Di(dimethylamino)acridine; Acridine Orangebase; Acridine orange free base; Brilliant Acridine Orange E; C.I. 46005B; C.I.Solvent Orange 15; NSC 194350; Solvent Orange 15; Waxoline Orange A
EINECS: 200-614-0
Density: 1.169 g/cm3
Melting Point: 165 °C (dec.)(lit.)
Boiling Point: 468.6 °C at 760 mmHg
Flash Point: 237.2 °C
Appearance: BROWN POWDER
Safety: Poison by subcutaneous route. Questionable carcinogen with experimental tumorigenic and carcinogenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
PSA: 19.37000
LogP: 3.52000
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    Molecular Formula: C17H19N3 Formula Weight: 265.35

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Chemistry

The MF of 3,6-BIS(DIMETHYLAMINO)ACRIDINE(494-38-2): C17H19N3
The MW of 3,6-BIS(DIMETHYLAMINO)ACRIDINE(494-38-2): 265.35
mp: 165 °C (dec.)(lit.)
Density: 1.169 g/cm3 
Flash Point: 237.2 °C 
Boiling Point: 468.6 °C at 760 mmHg 
Index of Refraction: 1.71 
Synonyms: 3,6-bis(dimethylamino)-acridin;3,6-bis-(dimethylamino)akridin;3,6-di(dimethylamino)acridine;acridineorangefreebase;acridrineorangebase;brilliantacridineorangee;c.i.46005b;c.i.no.46005
The Structure of 3,6-BIS(DIMETHYLAMINO)ACRIDINE(494-38-2):

Toxicity Data With Reference

1.   

mmo-omi 10 µg/L

   MIBLAO    Microbiology (Moscow). 49 (1980),223.
2.   

dns-rat:lvr 1 mmol/L

   ENMUDM    Environmental Mutagenesis. 3 (1981),11.
3.   

otr-ham:emb 1 µg/L

   NCIMAV    National Cancer Institute, Monograph. 58 (1981),243.
4.   

scu-mus LD50:250 mg/kg

   BJEPA5    British Journal of Experimental Pathology. 28 (1947),1.

Consensus Reports

IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 16 (1978),p. 145.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .

Safety Profile

Poison by subcutaneous route. Questionable carcinogen with experimental tumorigenic and carcinogenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Safety Statements: 22-24/25
22:  Do not breathe dust 
24/25:  Avoid contact with skin and eyes  
WGK Germany: 3
RTECS: AR7600000