Products Categories
CAS No.: | 498-00-0 |
---|---|
Name: | 4-Hydroxy-3-methoxybenzyl alcohol |
Article Data: | 165 |
Molecular Structure: | |
Formula: | C8H10O3 |
Molecular Weight: | 154.166 |
Synonyms: | Vanillylalcohol (6CI,8CI);3-Methoxy-4-hydroxybenzyl alcohol;4-(Hydroxymethyl)-2-methoxyphenol;4-Hydroxy-3-methoxybenzenemethanol;NSC 3993;V 0018;V 0018 (alcohol);Vanillicalcohol;Vanillin alcohol;p-(Hydroxymethyl)guaiacol;Benzenemethanol,4-hydroxy-3-methoxy-; |
EINECS: | 207-852-4 |
Density: | 1.226 g/cm3 |
Melting Point: | 110-117 ºC(lit.) |
Boiling Point: | 313.1 ºC at 760 mmHg |
Flash Point: | 143.2ºC |
Solubility: | Soluble in 95% ethanol (5 %), water, and oils. |
Appearance: | crystalline white to off-white powder |
Hazard Symbols: | Xi |
Risk Codes: | R36/37/38 |
Safety: | 26-36 |
PSA: | 49.69000 |
LogP: | 0.89310 |
4-hydroxymethyl-2-methoxyphenol
Conditions | Yield |
---|---|
With water | 100% |
Conditions | Yield |
---|---|
With hydrogen In water at 70℃; Catalytic behavior; | A 99.9% B n/a |
With hydrogen In water at 20 - 100℃; under 3750.38 Torr; for 1h; Kinetics; Reagent/catalyst; Temperature; Pressure; Autoclave; | A 90.9% B 9.1% |
With 2 wt% Pd/C; hydrogen In water at 20 - 100℃; under 3750.38 Torr; for 1h; Kinetics; Reagent/catalyst; Autoclave; | A 21.8% B 78.3% |
Conditions | Yield |
---|---|
With whole cells of recombinant strain VA1 In aq. phosphate buffer at 30℃; for 24h; pH=7.4; Temperature; Microbiological reaction; | 99.2% |
Conditions | Yield |
---|---|
With sodium tetrahydroborate In methanol for 1h; | 98% |
With aluminum oxide; zinc(II) tetrahydroborate In tetrahydrofuran at 20℃; for 0.08h; chemoselective reaction; | 97% |
With water; nickel dichloride; zinc In N,N-dimethyl-formamide for 2h; Ambient temperature; | 95% |
Conditions | Yield |
---|---|
With sodium tetrahydroborate; Trimethyl borate; dimethyl sulfate In tetrahydrofuran at 20℃; for 1.5h; | 98% |
With diisopropoxytitanium(III) tetrahydroborate In dichloromethane for 4h; Ambient temperature; | 73% |
With D-glucose In aq. phosphate buffer at 30℃; for 29h; pH=8; Enzymatic reaction; | 69% |
With hydrogen In aq. phosphate buffer at 50℃; under 3750.38 Torr; for 24h; pH=2; Autoclave; |
2-methoxy-4-((methoxymethoxy)methyl) phenol
4-hydroxymethyl-2-methoxyphenol
Conditions | Yield |
---|---|
With 1-methylimidazole hydrogen sulfate at 120℃; for 0.025h; Microwave irradiation; chemoselective reaction; | 95% |
phosphotungstic acid In ethanol for 4h; Heating; | 81% |
4-hydroxymethyl-2-methoxyphenol
Conditions | Yield |
---|---|
With silica gel In methanol at 60℃; for 3h; Inert atmosphere; | 95% |
3-methoxy-4-(2-propenyloxy) benzenemethanol
4-hydroxymethyl-2-methoxyphenol
Conditions | Yield |
---|---|
With cerium(III) chloride; sodium iodide In acetonitrile for 6h; deallylation; Heating; | 94% |
4-((ethoxymethoxy)methyl)-2-methoxy phenol
4-hydroxymethyl-2-methoxyphenol
Conditions | Yield |
---|---|
With 1-methylimidazole hydrogen sulfate at 120℃; for 0.0333333h; Microwave irradiation; chemoselective reaction; | 93% |
phosphotungstic acid In ethanol for 3h; Heating; | 91% |
4-hydroxymethyl-2-methoxyphenol
Conditions | Yield |
---|---|
bismuth(lll) trifluoromethanesulfonate In tetrahydrofuran; water at 20℃; for 0.5h; | 90% |
What can I do for you?
Get Best Price
IUPAC Name: 4-(Hydroxymethyl)-2-methoxyphenol
Empirical Formula: C8H10O3
Molecular Weight: 154.1632g/mol
EINECS: 207-852-4
Structure of 4-Hydroxy-3-methoxybenzyl alcohol (CAS NO.498-00-0):
Index of Refraction: 1.57
Molar Refractivity: 41.26 cm3
Molar Volume: 125.6 cm3
Polarizability: 16.35×10-24cm3
Surface Tension: 48.9 dyne/cm
Density: 1.226 g/cm3
Flash Point: 143.2 °C
Enthalpy of Vaporization: 58.51 kJ/mol
Melting Point: 110-117 °C(lit.)
Boiling Point: 313.1 °C at 760 mmHg
Vapour Pressure: 0.000216 mmHg at 25 °C
Stability: Stable. Incompatible with strong oxidizing agents, strong acids.
Product Categories: Benzhydrols, Benzyl & Special Alcohols
Canonical SMILES: COC1=C(C=CC(=C1)CO)O
InChI: InChI=1S/C8H10O3/c1-11-8-4-6(5-9)2-3-7(8)10/h2-4,9-10H,5H2,1H3
InChIKey: ZENOXNGFMSCLLL-UHFFFAOYSA-N
Safety Information of 4-Hydroxy-3-methoxybenzyl alcohol (CAS NO.498-00-0):
Hazard Codes: Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
WGK Germany: 3
Hazard Note: Irritant
4-Hydroxy-3-methoxybenzyl alcohol , its cas register number is 498-00-0. It also can be called 4-Hydroxy-3-methoxybenzenemethanol ; 4-Hydroxy-3-methoxybenzyl alcohol ; 4-Hydroxy-3-methoxyphenylmethanol ; AI3-24186 ; Benzenemethanol, 4-hydroxy-3-methoxy- ; Vanillic alcohol ; Vanillin alcohol ; Vanillyl alcohol . 4-Hydroxy-3-methoxybenzyl alcohol (CAS NO.498-00-0) is crystalline white to off-white powder .