CAS No.50-54-4,QUINIDINE SULFATE Suppliers

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Basic Information

Molecular Structure:
CAS No.:	50-54-4
Name:	QUINIDINE SULFATE

Formula:	C₄₀H₄₈N₄O₄•H₂O₄S
Molecular Weight:	746.925
Synonyms:	Quinidine bisulfate;Quinidine, sulfate (2:1) (salt);Quinitex;Cinchonan-9-ol,6'-methoxy-,(9S)-,sulfate (2:1) (salt);Auriquin;Quinidex;Quinidine sulfate anhydrous;Cin-Quin;Vanquin;Quinidate;QUINIDINE;Kinichron;(S)-[(4S,5S,7R)-5-ethenyl-1-azabicyclo[2.2.2]oct-7-yl]-(6-methoxyquinolin-4-yl)methanol; sulfuric acid;Cinchonan-9-ol, 6-methoxy-, (9S)-, sulfate (2:1) (salt);Quinidine monosulfate;Quinidine sulfate (salt);Cin quin;Quinora;Chinidine sulfate;Quinicardine;Quinidine sulfate;SK-Quinidine sulfate;Systodin;(9S)-6′-METHOXYCINCHONAN-9-OL SULFATE (2:1) (SALT);QUINIDINE SULPHATE;CINCHONAN-9-OL, 6′-METHOXY-, (9S)-, SULFATE (2:1) (SALT) (9CI);
EINECS:	200-046-3
Density:	g/cm³
Melting Point:	212°C
Boiling Point:	495.9°Cat760mmHg
Flash Point:	253.7°C
Hazard Symbols:	Xn
Risk Codes:	22
Safety:	Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Human systemic effects: arrythmias, cholestatic conjunctive irritation, cyanosis, death, distorted perceptions, dyspnea, fever, hallucinations, hepatitis, increased body temperature, irritative dermatitis, jaundice, joints effects, liver function impairment, other vascular and pulmonary changes, somnolence, transaminases changes, tremors, tumors. When heated to decomposition it emits very toxic fumes of NO_x and SO_x. See also QUINIDINE.
PSA:	174.16000
LogP:	6.65020

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Chemistry

MF: C₄₀H₅₀N₄O₈S
MW: 746.91
EINECS: 200-046-3
Product Categories: Organics
Melting Point Quinidinesulfate(2:1)(salt) (50-54-4):: 212°C
IUPAC Name: (S)-[(5R,7R)-5-ethenyl-1-azabicyclo[2.2.2]octan-7-yl]-(6-methoxyquinolin-4-yl)methanol ; sulfuric acid
Synonyms: Quinidinemono sulfate ; (9S)-6’-methoxycinchonan-9-olsulfate(2:1)(salt) ; 6’-Methoxy-cinchonan-9-o(9s)-cinchonan-9-osulfate(2:1)(salt) ; 6’-Methoxycinchonan-9-olsulfate ; Chinidinesulfate ; Quinidate ; Quinidinemonosulfate ; Quinidinesulfate(2:1)(salt)
Following is the molecular structure of Quinidinesulfate(2:1)(salt) (50-54-4):

Toxicity Data With Reference

1.	orl-man TDLo:240 mg/kg/2W-I:EYE	JTCTDW Journal of Toxicology, Clinical Toxicology. 20 (1983),367.
2.	orl-wmn TDLo:272 mg/kg/17D-I:CVS	AIMDAP Archives of Internal Medicine. 145 (1985),2051.
3.	orl-man TDLo:40 mg/kg/2W-I:CVS	AIMDAP Archives of Internal Medicine. 145 (1985),2051.
4.	orl-hmn TDLo:9600 mg/kg/8W:CNS,PUL	JAMAAP JAMA, Journal of the American Medical Association. 238 (1977),884.
5.	orl-wmn TDLo:409 g/kg/14Y:CNS	JAMAAP JAMA, Journal of the American Medical Association. 237 (1977),2093.
6.	orl-man TDLo:88 mg/kg/10D-I:SYS	GASTAB Gastroenterology. 70 (1976),1136.
7.	orl-wmn TDLo:32 mg/kg/2D:SKN	DICPBB Drug Intelligence and Clinical Pharmacy. 16 (1982),615.
8.	mul-man LDLo:30 mg/kg/2D-I:CVS,PUL	AIMEAS Annals of Internal Medicine. 16 (1942),571.
9.	orl-rat LD50:456 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 18 (1968),1127.
10.	ipr-rat LDLo:140 mg/kg	TXAPA9 Toxicology and Applied Pharmacology. 1 (1959),156.

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Human systemic effects: arrythmias, cholestatic conjunctive irritation, cyanosis, death, distorted perceptions, dyspnea, fever, hallucinations, hepatitis, increased body temperature, irritative dermatitis, jaundice, joints effects, liver function impairment, other vascular and pulmonary changes, somnolence, transaminases changes, tremors, tumors. When heated to decomposition it emits very toxic fumes of NO_x and SO_x.
Safety Information of Quinidinesulfate(2:1)(salt) (50-54-4):
Risk Statements: 22
22: Harmful if swallowed
Safety Statements: 22-45
22: Do not breathe dust
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR: 1544