Detail of "5001-98-9"

CAS Number:
5001-98-9
Name:
[1,1'-Biphenyl]-4-aceticacid, 2'-chloro-
Molecular Structure:
Formula:
C₁₄H₁₁ClO₂
Molecular Weight:
246.69
Synonyms:
4-Biphenylaceticacid, 2'-chloro- (8CI);Acetic acid, (2'-chloro-4-biphenylyl)- (7CI);F 2006;
Density:
1.27 g/cm³
Boiling Point:
399.8 °C at 760 mmHg
Flash Point:
195.6 °C

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Pharmacokinetic and metabolic study of itanoxone in man: Pharmacokinetic and metabolic study of itanoxone in man. Bret, M. C.; Chanal, J. L.; Marignan, R.; Monnier, L.; Poitou, P.; Cousse, H.; Fauran, F. (Fac. Pharm., Montpellier 34000, Fr.). Therapie, 39(4), 345-52 (French) 1984. CODEN: THERAP. ISSN: 0040-5957. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) The pharmacokinetics of itanoxone (I) [58182-63-1] were studied under clin. conditions. After a single oral dose (500 mg) of the drug, max. plasma levels were obsd. only after ~4 h. Elimination of the drug was biphasic, with a terminal half-life of 13.5 h. No accumulation was obsd. after repeated doses. 2'-Chlorobiphenyl-p-carboxylic acid [3808-93-3], 2'-chlorobiphenyl-p-acetic acid [5001-98-9], and 2'-chloro-4'-hydroxybiphenyl-p-acetic acid [94039-70-0] were identified as blood and urinary metabolites of itanoxone. A metabolic pathway is proposed.