Detail of "508-77-0"

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CAS Number:
508-77-0
Name:
Card-20(22)-enolide,3-[(2,6-dideoxy-3-O-methyl-b-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxo-, (3b,5b)-
Molecular Structure:
Formula:
C30H44 O9
Molecular Weight:
548.74
Deleted CAS:
88195-73-7
Synonyms:
Cymarin(6CI,7CI,8CI);Alvonal MR;Cymarine;K-Strophanthin-a;NSC 7522;Strophantin K;WV 90043a;
Density:
1.31 g/cm3
Melting Point:
148ºC
Boiling Point:
722.1ºCat 760 mmHg
Flash Point:
232.7 ºC
Hazard Symbols:
T
Risk Codes:
23/25-33
Safety:
Poison by intravenous, intraperitoneal, and possibly other routes. Used as a cardiotonic. When heated to decomposition it emits acrid smoke and fumes. Details

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Study of Adonis turkestanica (Korsch) Adolf: Study of Adonis turkestanica (Korsch) Adolf. Evdokimov, P. K.; Nazirov, Z. N. (Tashk. Farm. Inst., Tashkent, USSR). Med. Zh. Uzb., (8), 44-7 (Russian) 1977. CODEN: MZUZA8. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 11 A. turkestanica showed highest biol. activity during flowering and fruit formation (80-150 frog units). Circadial activity cycle had max. at 7 a.m. and 8 p.m., and a min. at 2 a.m. The cardenolide const. was highest in undergroun organs, green fruits, and upper leaves. The main glycosides were cymarin [508-77-0] and k-strophanthin-.beta. [560-53-2]. The plants contained 0.5-1.0% flavonoids, 0.01-0.02% coumarins, 0.8-1.2% org. acids, 6.8-8.2% amino acids, 1.3-1.79% reducing sugars (glucose [50-99-7], rhamnose [3615-41-6], arabinose [147-81-9], and 2 unidentified), 0.4-0.51% lipids, 3.1-3.3% resins, 3-5.5% adonitol [488-81-3], 2.7-3.0% carbohydrates, 0.77% salicylic acid [69-72-7], 0.2% tartaric acid [87-69-4], 0.08% citric acid [77-92-9], 0.02% oxalic acid [144-62-7], and 0.08% lactic acid [50-21-5]. Orientin [28608-75-5], homoorientin [39319-16-9], adonivernite [22150-36-3], and luteolin [491-70-3] were found.

Gas-chromatographic determination of methanol and water in standard cymarin: Gas-chromatographic determination of methanol and water in standard cymarin. Rosik, G. G.; Grizodub, A. I.; Kazarinov, N. A.; Evtushenko, N. S.; Chichiro, V. E. (Vses. Nauchno-Issled. Inst. Khim. Tekhnol. Lek. Sred., Moscow, USSR). Khim.-Farm. Zh., 17(12), 1516-19 (Russian) 1983. CODEN: KHFZAN. ISSN: 0023-1134. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) MeOH [67-56-1] and water, used for the purifn. of the digitalis glycoside std. cymarin [508-77-0], was detd. by gas chromatog. with Polysorb (0.2-0.5 mm) as the stationary phase, with thermal cond. detectors and He as the carrier gas. EtOH was used as the internal std. Statistical treatment of results is given for calcn. of the amts. of MeOH and H2O.