Detail of "50889-46-8"

Reference

6-Keto- and 6-hydroxy-8-azaprostanoids and their anti-ulcer use

6-Keto- and 6-hydroxy-8-azaprostanoids and their anti-ulcer use. Wang, Chia Lin J. (du Pont de Nemours, E. I., and Co. , USA). U.S. US 4456613 A 26 Jun 1984, 10 pp. (English). (United States of America). CODEN: USXXAM. CLASS: IC: A61K031-40; C07D207-27. NCL: 424274000.Except for chemicals metioned above, 50889-46-8 is also used. APPLICATION: US 82-452883 27 Dec 1982. DOCUMENT TYPE: Patent CA Section: 26 (Biomolecules and Their Synthetic Analogs) Title compds. 50889-46-8 which is the cas registry number of some chemical is mentioned. I [X = O or (H,OH); R = CH2OH, carboxy, C1-12 alkyl or cycloalkyl ester; R1 = H, Me, Et; R2 = H, Me, F; R3 = Me, CF3; n = 3-8] were prepd. by appropriate modifications of conventional methods, with Me 5-oxo-2-pyrrolidinecarboxylate as the ring building block; they had ulcer cytoprotective activity. Typical of compds. prepd. was the 11-deoxy-6-oxo-8-aza-PGE1 analog II. ..

6-Keto- and 6-hydroxy-8-azaprostanoids and their anti-ulcer use

6-Keto- and 6-hydroxy-8-azaprostanoids and their anti-ulcer use. Wang, Chia Lin J. (du Pont de Nemours, E. I., and Co. , USA). U.S. US 4456613 A 26 Jun 1984, 10 pp. (English). (United States of America). CODEN: USXXAM. CLASS: IC: A61K031-40; C07D207-27. NCL: 424274000.Except for chemicals metioned above, 50889-46-8 is also used. APPLICATION: US 82-452883 27 Dec 1982. DOCUMENT TYPE: Patent CA Section: 26 (Biomolecules and Their Synthetic Analogs) Title compds. 50889-46-8 which is the cas registry number of some chemical is mentioned. I [X = O or (H,OH); R = CH2OH, carboxy, C1-12 alkyl or cycloalkyl ester; R1 = H, Me, Et; R2 = H, Me, F; R3 = Me, CF3; n = 3-8] were prepd. by appropriate modifications of conventional methods, with Me 5-oxo-2-pyrrolidinecarboxylate as the ring building block; they had ulcer cytoprotective activity. Typical of compds. prepd. was the 11-deoxy-6-oxo-8-aza-PGE1 analog II. ..