Detail of "51-43-4"

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CAS Number:
51-43-4
Name:
L(-)-Epinephrine
Molecular Structure:
Formula:
C₉H₁₃NO₃
Molecular Weight:
183.20
Deleted CAS:
51028-73-0
Synonyms:
1,2-Benzenediol,4-[1-hydroxy-2-(methylamino)ethyl]-, (R)-;Benzyl alcohol, 3,4-dihydroxy-a-[(methylamino)methyl]-, (-)-(8CI);(-)-(R)-Epinephrine;(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol;(-)-Adrenaline;(-)-Epinephrine;(R)-Adrenaline;(R)-Epinephrine;Adnephrine;Adrenal;Adrenalin;Adrenaline;Adrenine;Bronkaid Mist;Chelafrin;Epifrin;Epinefrina;Epinephran;Exadrin;Glauposine;Hemisine;Isoptoepinal;L-Adrenaline;Levoepinephrine;Levorenen;Levoreninum;Lyodrin;Methylarterenol;N-[(2R)-2-(3,4-Dihydroxyphenyl)-2-hydroxyethyl]-N-methylamine;NSC 62786;Paranephrin;R-(-)-Epinephrine;Renaglandin;Renalina;Renoform;Renostypticin;Scurenaline;Styptirenal;Supranephrane;Suprarenaline;Vasoconstrictine;Vasotonin;l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol;l-Epinephrine;
EINECS:
200-098-7
Density:
1.283 g/cm³
Melting Point:
215 °C (dec.)(lit.)
Boiling Point:
413.1 °C at 760 mmHg
Flash Point:
207.9 °C
Solubility:
<0.01 g/100 mL at 18 °C
Appearance:
off-white powder
Hazard Symbols:
T
Risk Codes:
23/24/25-52/53-36/37/38-33
Safety:
36/37/39-45-61-26-23 Details
Transport Information:
UN 2811 6.1/PG 2

Appearance:white powder

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Effect of epinephrine upon irreversible disposal and recycling of glucose in dogs: Effect of epinephrine upon irreversible disposal and recycling of glucose in dogs. Forichon, J.; Jomain, M. J.; Schelhorn, J.; Minaire, Y. (Lab. Thermoregul., CNRS, Lyon, Fr.). Experientia, 33(9), 1171-3 (English) 1977. CODEN: EXPEAM. DOCUMENT TYPE: Journal CA Section: 2 (Hormone Pharmacology) Irreversible utilization and recycling of glucose [50-99-7] during epinephrine (I) [51-43-4]-induced hyperglycemia were studied in adrenal-demedullated dogs exposed to neutral or cold ambient temp. Whatever the ambient temp., most of the extra glucose mobilized by I was recycled, rather than irreversibly utilized by the peripheral tissues.

Cardiovascular responses to centrally administered adrenaline in spontaneous hypertensive rats: Cardiovascular responses to centrally administered adrenaline in spontaneous hypertensive rats. Borkowski, K. R.; Finch, L. (Postgrad. Sch. Stud. Pharmacol., Univ. Bradford, Bradford, Engl.). Br. J. Pharmacol., 61(1), 130P (English) 1977. CODEN: BJPCBM. DOCUMENT TYPE: Journal CA Section: 2 (Hormone Pharmacology) Adrenaline [51-43-4] [1-20 mg, intracerebroventricularly (i.c.v.)] caused a dose-related fall in blood pressure and heart rate in spontaneous hypertensive rats. Pretreatment with phentolamine (100 mg, i.c.v.) did not antagonize the adrenaline-induced hypotension and bradycardia, but (±)-propranolol, sotalol, or metoprolol (all 100 mg, i.c.v.) pretreatment completely abolished these effects, suggesting that b-adrenoceptors were involved.