CAS No.51012-33-0,Tiapride hydrochloride Suppliers

Products Categories

Pharmaceutical (42)
Organic Chemicals (14)
Others (6)
Reagent (2)
Basic Inorganic Chemicals (2)

Basic Information

Molecular Structure:
CAS No.:	51012-33-0
Name:	Tiapride hydrochloride

Formula:	C15H24 N2 O4 S . Cl H
Molecular Weight:	364.894
Synonyms:	Benzamide,N-[2-(diethylamino)ethyl]-2-methoxy-5-(methylsulfonyl)-, monohydrochloride(9CI); Gramalil; Italprid; Luxoben; Sereprile; Tiapridal; Tiapridehydrochloride; Tiapridex
EINECS:	256-908-4
Density:	1.15 g/cm³
Melting Point:	approximate 200℃ (dec.)
Boiling Point:	498.1 °C at 760 mmHg
Flash Point:	255.1 °C
Safety:	Poison by ingestion, intravenous, and intraperitoneal routes. Moderately toxic by subcutaneous route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SO_x, NO_x, and HCl.
PSA:	84.09000
LogP:	3.44400

Total:58 Page 1 of 2 1 2 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 51012-33-0

Chemistry

UPAC Name: N-(2-diethylaminoethyl)-2-methoxy-5-methylsulfonylbenzamide hydrochloride (51012-33-0)
SynonymsTtiapride hydrochloride ; N-[2-(diethylamino)ethyl]-5-[methyl-sulfonyl]-o-anisamide hydrochloride ; N-(2-(diethylamino)ethyl)-2-methoxy-5-(methylsulfonyl)benzamidehydrochloride ; N-(2-(diethylamino)ethyl)-2-methoxy-5-(methylsulfonyl)-benzamidmonohydroch ; N-(2-(diethylamino)ethyl)-2-methoxy-5-(methylsulfonyl)-benzamidmonohydrochloride ; N-[2-(diethylamino)ethyl]-2-methoxy-5-(methylsulphonyl)benzamide monohydrochloride ; TiapridHCl;Tiapridhydrochlorid
CAS: 51012-33-0
MF: C₁₅H₂₅ClN₂O₄S
MW: 364.89
MS:
EINECS: 256-908-4
Mol File: 51012-33-0.mol
Flash Point: 255.1 °C
Enthalpy of Vaporization: 76.63 kJ/mol
Boiling Point: 498.1 °C at 760 mmHg
Vapour Pressure: 4.65E-10 mmHg at 25°C
Storage temp: StoreTiapride hydrochloride (51012-33-0) at 2-8°C.

Uses

Tiapride hydrochloride (51012-33-0）is antipsychotics.

Production

Tiapride hydrochloride (51012-33-0）is prepared by reacting 2-methoxy-5-methylsulfonylbenzoic acid (I) with isobutyl chloroformate (A) in dioxane to give the corresponding anhydride (II), which is finally condensed with N,N-diethylethylenediamine (B).

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	240mg/kg (240mg/kg)	sense organs and special senses: mydriasis (pupillary dilation): eye sense organs and special senses: ptosis: eye behavioral: somnolence (general depressed activity)	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 1933, 1985.
mouse	LD50	intraperitoneal	336mg/kg (336mg/kg)	behavioral: altered sleep time (including change in righting reflex) behavioral: somnolence (general depressed activity) behavioral: convulsions or effect on seizure threshold	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 1933, 1985.
mouse	LD50	intravenous	189mg/kg (189mg/kg)	behavioral: altered sleep time (including change in righting reflex) behavioral: convulsions or effect on seizure threshold behavioral: somnolence (general depressed activity)	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 1933, 1985.
mouse	LD50	oral	1340mg/kg (1340mg/kg)	behavioral: altered sleep time (including change in righting reflex) behavioral: somnolence (general depressed activity) behavioral: convulsions or effect on seizure threshold	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 1933, 1985.
mouse	LD50	subcutaneous	755mg/kg (755mg/kg)	behavioral: altered sleep time (including change in righting reflex) behavioral: convulsions or effect on seizure threshold ehavioral: somnolence (general depressed activity)	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 1933, 1985.
rat	LD50	intraperitoneal	421mg/kg (421mg/kg)	sense organs and special senses: ptosis: eye behavioral: somnolence (general depressed activity) behavioral: convulsions or effect on seizure threshold	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 1933, 1985.
rat	LD50	intravenous	254mg/kg (254mg/kg)	sense organs and special senses: ptosis: eye behavioral: somnolence (general depressed activity) behavioral: convulsions or effect on seizure threshold	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 1933, 1985.
rat	LD50	oral	4840mg/kg (4840mg/kg)	sense organs and special senses: ptosis: eye behavioral: somnolence (general depressed activity) behavioral: convulsions or effect on seizure threshold	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 1933, 1985.
rat	LD50	subcutaneous	1130mg/kg (1130mg/kg)	sense organs and special senses: ptosis: eye behavioral: somnolence (general depressed activity) behavioral: convulsions or effect on seizure threshold	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 1933, 1985.

Safety Profile

WGK Germany: 2
RTECS: CV4203800