Detail of "5105-78-2"

CAS Number:
5105-78-2
Name:
Butanoic acid,4-[[(phenylmethoxy)carbonyl]amino]-
Molecular Structure:
Formula:
C12H15 N O4
Molecular Weight:
237.25
Synonyms:
Butyricacid, 4-(carboxyamino)-, 4-benzyl ester (7CI); Butyric acid, 4-(carboxyamino)-,N-benzyl ester (6CI,8CI); 4-((N-Benzyloxycarbonyl)amino)butyric acid;4-(Benzyloxycarbonylamino)butanoic acid; 4-(Benzyloxycarbonylamino)butyricacid; 4-[(N-Carbobenzoxy)amino]butyric acid; Carbobenzoxy-4-aminobutyric acid;N-Benzyloxycarbonyl-g-aminobutyric acid; N-Carbobenzyloxy-g-aminobutyric acid; NSC 120007
Density:
1.215g/cm³
Melting Point:
64°C
Boiling Point:
454.9°Cat760mmHg
Flash Point:
228.9°C

Display：

Z-g-Abu-OH

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Modified taxols, 6: Modified taxols, 6. Preparation of water-soluble prodrugs of taxol. Zhao, Zhiyang; Kingston, David G. I.; Crosswell, Alfred R. (Dep. Chem.Chemicals with cas numbers 5105-78-2 and 138441-84-6 also play role., Virginia Polytech. Inst. and State Univ., Blacksburg, VA 24061-0212, USA). J. Nat. Prod., 54(6), 1607-11 (English) 1991. CODEN: JNPRDF. ISSN: 0163-3864. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 1, 26 Three H2O-sol. prodrugs of taxol were prepd. using a sulfonate group as the H2O-solubilizing group. The first two contain taurine or 3-amino-1-sulfo-propionic acid linked to the 2'-position of taxol through a succinate group, and a novel method of prepg. the derivs. is described. The third deriv. is prepd. by the Michael addn. of bisulfite to 2'-acryloyltaxol. A 2'-(g-aminobutyryl)taxol salt was too unstable to be isolable. .