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Detail of "5140-72-7"

  • MSDS Download
  • CAS Number:
  • 5140-72-7
  • Name:
  • Pyridine,2-bromo-6-chloro-

  • Superlist Name:
  • 2-Bromo-6-chloropyridine
  • Molecular Structure:
  • Formula:
  • C5H3BrClN
  • Molecular Weight:
  • 192.44
  • Synonyms:
  • 2-Bromo-6-chloropyridine;6-Bromo-2-chloropyridine;
  • EINECS:
  • 225-904-4
  • Density:
  • 1.736 g/cm3
  • Melting Point:
  • 90-91 °C
  • Boiling Point:
  • 230.8 °C at 760 mmHg
  • Flash Point:
  • 93.4 °C
  • Hazard Symbols:
  • IrritantXi,HarmfulXn
  • Risk Codes:
  • 22-36/37/38
  • Safety:
  • 26-36/37-36/37/39 Details

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CAS No.5140-72-7 2-Bromo-6-chloropyridine

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CAS No.5140-72-7 2-Bromo-6-chloropyridine

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CAS No.5140-72-7 2-Bromo-6-chloropyridine

2-BROMO-6-CHLOROPYRIDINE

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CAS No.5140-72-7 2-Bromo-6-chloropyridine

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2-Bromo-6-chloropyridine

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CAS No.5140-72-7 2-Bromo-6-chloropyridine

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CAS No.5140-72-7 2-Bromo-6-chloropyridine

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Reference

Synthesis of novel halopyridinylboronic acids and esters
Synthesis of novel halopyridinylboronic acids and esters. Part 4: Halopyridin-2-yl-boronic acids and esters are stable, crystalline partners for classical Suzuki cross-coupling. Bouillon, Alexandre; Lancelot, Jean-Charles; Santos, Jana Sopkova de Oliveira; Collot, Valerie; Bovy, Philipppe R.; Rault, Sylvain (UFR des Sciences Pharmaceutiques, Centre d'Etudes et de Recherche sur le Medicament de Normandie, Caen 14032, Fr.). Tetrahedron, 59(50), 10043-10049 (English) 2003 Elsevier Science B.V. CODEN: TETRAB. ISSN: 0040-4020. DOCUMENT TYPE: Journal CA Section: 29 (Organometallic and Organometalloidal Compounds) Methods for the synthesis and the isolation of novel 5 or 6-halopyridin-2-yl-boronic acids and esters I and II (R = 5-Cl, 5-Br, 6-Cl, 6-Br). These compds. were prepd. 5140-72-7 and 652148-96-4 which are cas registry numbers of chemicals are mentioned. via a regioselective halogen-metal exchange using BuLi and subsequent quenching with triisopropylborate starting from appropriate dihalopyridines. All substrates studied to date provided a single regioisomeric boronic acid or ester product. Addnl., these compds. undergo Pd-catalyzed coupling with arylhalides and authorize a strategy to produce new pyridine libraries. .
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