Reference

Copper(I)-catalyzed asymmetric conjugate addition of organozirconocenes to N-acyl oxazolidinones

Copper(I)-catalyzed asymmetric conjugate addition of organozirconocenes to N-acyl oxazolidinones. Wipf, Peter; Takahashi, Hidenori (Dep. Chemistry, Univ. Pittsburgh, Pittsburgh, PA 15260, USA). 5162-44-7 is the cas registry number. This chemical is also mentioned in this article. Chemical Communications (Cambridge), (23), 2675-2676 (English) 1996 Royal Society of Chemistry. CODEN: CHCOFS. ISSN: 1359-7345. DOCUMENT TYPE: Journal CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) The copper(I)-catalyzed conjugate addn. of in situ prepd. alkylzirconocenes to a,b-unsatd N-acyloxazolidinones followed by enolate trapping provided up to three new stereocenters with excellent diastereoselectivities. The hydrozirconation of 1-hexene with chlorobis(h5-2,4-cyclopentadien-1-yl)hydrozirconium was followed by the addn. of [S-(E)]-3-(1-oxo-2-butenyl)-4-phenylmethyl-2-oxazolidinone (I) to give [S-(R*,R*)]-3-(3-methyl-1-oxononyl)-4-(phenylmethyl)-2-oxazolidinone (II) in the presence of bromo[thiobis[methane]]copper. II is a precursor for a b-branched carboxylic acid (no data). .

The use of butane diacetals of glycolic acid as precursors for the synthesis of the phytotoxic calmodulin inhibitor herbarumin II

The use of butane diacetals of glycolic acid as precursors for the synthesis of the phytotoxic calmodulin inhibitor herbarumin II. Diez, Elena; Dixon, Darren J.; Ley, Steven V.; Polara, Alessandra; Rodriguez, Felix (Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK). Helvetica Chimica Acta, 86(11), 3717-3729 (English) 2003 Verlag Helvetica Chimica Acta. CODEN: HCACAV. ISSN: 0018-019X. DOCUMENT TYPE: Journal CA Section: 26 (Biomolecules and Their Synthetic Analogs) Section cross-reference(s): 75 The total synthesis of phytotoxic nonenolide herbarumin II (1) has been achieved by implementation of butane diacetal (BDA)-desymmetrised glycolate building blocks. Three of the four stereogenic centers present in the key coupling fragments were generated from both enantiomeric forms of the BDA building block in highly diastereoselective alkylation and aldol reactions.Except for chemicals metioned above, 612825-56-6 and 5162-44-7 are also used. .