Reference

Toxicological properties of diosmin and its actions on the isolated venous tissue of the dog

Toxicological properties of diosmin and its actions on the isolated venous tissue of the dog. Heusser, J.; Osswald, W. (Wissenschaftl. Lab., Hommel A.-G., Adliswil, Switz.). Arch. Farmacol. Toxicol., 3(1), 33-40 (English) 1977. CODEN: AFTOD7. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) Section cross-reference(s): 1 Extpl. animals receiving oral doses of diosmin (I) [520-27-4] exhibited no subchronic (200 mg/kg, daily for 50 days), chronic (60-620 mg/kg, daily for 196 days), or teratogenic toxic effects. I caused no change in the tone of saphenous vein strips from dogs and had no influence (20 .mu.g/mL) on the sensitivity of the strips to noradrenaline. Using oil immersion techniques, 20-100 .mu.g I/mL was shown to decrease the rate of relaxation of the strips after exposure to maximal contracting doses of noradrenaline.

Removal of musty odor by ozonization

Removal of musty odor by ozonization. Niituma, Keiju; Kiridoshi, Yukio; Sakamoto, Kouiti; Otsuka, Tadayo (Water Exam. Lab., Osaka Munic. Water Works Bur., Osaka, Japan). Osakashi Suidokyoku Komubu Suishitsu Shikensho Chosa Hokoku Narabini Shiken Seiseki, Volume Date 1974, 26, 15-21 (Japanese) 1976. CODEN: OSKSDF. DOCUMENT TYPE: Journal CA Section: 61 (Water) The musty oder of water from Lake Biwa was 50% removed by ozonization. Residual O3 was <0.1 ppm after treatment for 90 min at pH 6.8. Diosmin [520-27-4], one of the musty odor components, was decompd. by 31-50% after treatment with 10 ppm O3 for 3 min. No more decompn. was obsd. with more O3. Activated charcoal was also effective.