Detail of "522-66-7"

Reference

The quality of New Zealand's pharmaceuticals

The quality of New Zealand's pharmaceuticals. (MEDIQUAL Program). X. A survey of quinine and quinidine tablets. Harvey, H. E.; Heenan, M. P.; Passl, W. J. (Chem. Div., DSIR, Lower Hutt, N. Z.). Rep. - N. Z., Dep. Sci. Ind. Res., Chem. Div., C.D. 2229, 22 pp. (English) 1976. CODEN: NZCRA7. DOCUMENT TYPE: Report CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 64 Eighteen samples of quinine (I) and quinidine (II) tablets were examd. for compliance with the British Pharmacopeia and for their contents of dihydroquinine [522-66-7] and dihydroquinidine [1435-55-8]. Five samples complied fully with the requirements, 2 samples failed, and 11 samples had minor shortcomings. This work is preceded by a discussion on the treatment of malaria and on the pharmacol., pharmacokinetics and metab., toxicol., and anal. of the title compds.

Identification of alkaloids and anthraquinones in Cinchona pubescens callus cultures; the effect of plant growth regulators and light on the alkaloid content

Identification of alkaloids and anthraquinones in Cinchona pubescens callus cultures; the effect of plant growth regulators and light on the alkaloid content. Mulder-Krieger, T.; Verpoorte, R.; Van der Kreek, M.; Svendsen, A. Baerheim (Dep. Pharmacog., State Univ. Leiden, Leiden 2300 RA, Neth.). Planta Med., 50(1), 17-20 (English) 1984. CODEN: PLMEAA. ISSN: 0032-0943. DOCUMENT TYPE: Journal CA Section: 5 (Agrochemical Bioregulators) Section cross-reference(s): 11, 63 Alkaloids, e.g., cinchonine [118-10-5], cinchonidine [485-71-2], quinine [130-95-0], quinidine [56-54-2], dihydrocinchonine [485-65-4], dihydrocinchonidine [485-64-3], dihydroquinine [522-66-7], dihydroquinidine [1435-55-8], cinchonamine [482-28-0], 10-methoxycinchonamine [83852-64-6], quinamine [464-85-7], 3a,17b-cinchophylline [1355-62-0], 3a,17a-cinchophylline [10438-17-2] cinchoninone [14509-68-3], and quinidinone [14528-53-1], and anthraquinones, e.g. 1-hydroxy-2-hydroxymethylanthraquinone [24094-45-9], 1,8-dihydroxyanthraquinone [117-10-2], alizarin [72-48-0], alizarin 1-Me ether [6170-06-5], and rubiadin [117-02-2] were detected in C. pubescens leaf and stem cultures and their amts. depended on the type and compn. of culture medium and on the light stimulation. A medium contg. zeatin [1637-39-4] and 2,4-D [94-75-7] (1 mM each) gave a higher alkaloid prodn. than media contg. BA [1214-39-7] (8.1 mM) and 2,4-D (4.5 mM). Light stimulated alkaloids prodn. in callus cultures.