Detail of "52263-47-5"

CAS Number:
52263-47-5
Name:
2-(6-Chloro-9H-carbazol-2-yl)propanoic acid
Molecular Structure:
Formula:
C₁₅H₁₂ClNO₂
Molecular Weight:
273.7143
Synonyms:
6-Chlor-alpha-methyl-carbazol-2-essigsaeure [German];6-Chloro-alpha-methylcarbazole-2-acetic acid;6-Chloro-alpha-methyl-9H-carbazole-2-acetic acid;Carprofen;
Density:
1.42g/cm³
Boiling Point:
509.1 °C at 760 mmHg
Flash Point:
261.7 °C

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Determination of (d,l)-6-chloro-a-methylcarbazole-2-acetic acid in plasma by high-performance liquid chromatography: Determination of (d,l)-6-chloro-a-methylcarbazole-2-acetic acid in plasma by high-performance liquid chromatography. Palmskog, Goran; Hultman, Eric (Dep. Clin. Chem., Stockholm, Swed.). J. Chromatogr., 140(3), 310-15 (English) 1977. CODEN: JOCRAM. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Ro 20-5720 (d,l-6-chloro-a-methylcarbazole-2-acetic acid)(I) [52263-47-5] of blood plasma was detd. by extn. with di-Et ether followed by high-performance liq. chromatog. A m Bondapak C18 sepn. column was used, and the mobile phase was a water-methanol mixt. contg. tetrabutylammonium hydroxide. I was quantitated with a fluorescence detector having an excitation wavelength of 300 nm and a 370 nm cutoff filter. 52263-47-5 which is the cas registry number of one of substances is just one of reagents here. There was no interference from a no. of other antiinflammatory agents or from a metabolite of I. Although salicylates were detectable by this method, they appeared right after the front and did not interfere in the measurement of I. Recovery of added drug (1.5-15 mmol/L) was 84-94% using a 100-mL sample of plasma. .