Reference

Pattern of molecular aggregation of ginsenosides in aqueous solution

Pattern of molecular aggregation of ginsenosides in aqueous solution. Park, Hoon; Lee, Mee Kyoung; Park, Qwi Hee (Korea Ginseng Tob. Res. Inst., Daejeon, S. Korea). Han'guk Nonghwa Hakhoechi, 29(2), 198-206 (English) 1986. CODEN: JKACA7. ISSN: 0368-2897. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Micelle formation of ginsenosides in aq. solns. of purified saponins of Panax ginseng root was studied by dialysis through a tubing (MW 12,000) or elution through Bio-Gel P-2 (MW 200-2,000) and anal. for ginsenosides by HPLC. Ginsenosides can be classified into 3 groups depending upon mol. aggregation pattern and spatial arrangement of the hydrophilic parts (HPs) in mol. Group I, large micelle formers (aggregation no. >10) with one side having a HP, includes ginsenoside Rb1 [41753-43-9], Rb2 [11021-13-9], Rc [11021-14-0], and Rd [52705-93-8] (diols). Group II, small micelle formers (aggregation no. >10-1) having semi-two side HPs, includes Rg2 [52286-74-5], Rf [52286-58-5] (triol), and Rg3 [14197-60-5] (diol). Group III, no micelle former (aggregation no.: 1) with two side HPs, includes Re [52286-59-6] and Rg1 [22427-39-0] (triol).

Quantitative gas chromatography of panaxadiols and panaxatriols: qualitative evaluation of ginseng root and its preparation

Quantitative gas chromatography of panaxadiols and panaxatriols: qualitative evaluation of ginseng root and its preparation. Brieskorn, C. H.; Mosandl, A. (Inst. Pharm. Lebensmittelchem., Univ. Suerzburg, Wuerzburg, Ger.). Sci. Pharm., 46(2), 106-16 (German) 1978. CODEN: SCPHA4. ISSN: 0036-8709. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) The concns. of ginsenoside Rb1 [41753-43-9] and ginsenoside Re [52286-59-6] (detd. as panaxadiol and panaxatriol) in 15 com. ginseng prepns. varied from 2.8 mg to 1847 mg and 2.9 mg to 1355.5 mg/100 g, resp., and from 336.8 mg to 2475 mg and from 267.2 mg to 1355.5 mg/100 g declared ginseng root content, resp. Oleanolic acid formed during the acid hydrolysis of the ginsenosides to panaxadiol and panaxatriol was removed by ion exchange. Panaxadiol and panaxatriol were detd. by gas chromatog. with 3% SE 30 on chromosorb W, AW-DMCS.