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Detail of "523-50-2"

  • MSDS Download
  • CAS Number:
  • 523-50-2
  • Name:

  • 2H-Furo[2,3-h]-1-benzopyran-2-one

  • Superlist Name:
  • Angelicin
  • Molecular Structure:
  • Formula:
  • C11H6O3
  • Molecular Weight:
  • 186.16
  • Deleted CAS:
  • 39310-13-9
  • Synonyms:
  • Isopsoralen(6CI);2-Propenoic acid, 3-(4-hydroxy-5-benzofuranyl)-, d-lactone;Angecin;Angelicin (coumarin derivative);Furo[2,3-h]coumarin;Furo[5',4':7,8]coumarin;NSC 404563;Isopsoralen;
  • Density:
  • 1.389 g/cm3
  • Melting Point:
  • 132-134 °C
  • Boiling Point:
  • 362.6 °C at 760 mmHg
  • Flash Point:
  • 173.1 °C
  • Appearance:
  • white solid
  • Hazard Symbols:
  • HarmfulXn,IrritantXi
  • Risk Codes:
  • 20/21/22-36/37/38-40
  • Safety:
  • 26-36/37/39 Details
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CAS No.523-50-2 Angelicin

Assay:≥95%  Package:10 mg/vial, ...Storage:Preserve in ...

Model Number: WuXiRS A0028 Packaging & Delivery Delivery Detail Immediate export after the contract confirmed. Specifications This reference standard material is extracted and isolated from natural plant. Molecular Formula: C11H6O3 Molecular Weight: 186.2 Shelf life: Two

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CAS No.523-50-2 Angelicin

Assay:≥98%HPLC  Package:20mg;50mg;10...Storage:Store in dry...  Application:Analytical S...

Angelicin

Supplier:STANFORD CHEMICALS [ United States]

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CAS No.523-50-2 Angelicin

Assay:98%  Appearance:powder or cr...  Package:10mg,20mg,1g...Storage:-20degree

Supplier:shanghai Tauto Biotech Co., Ltd [ China (Mainland)]

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CAS No.523-50-2 Angelicin

Assay:98%

Supplier:Hangzhou Dayangchem Co., Ltd. [ China (Mainland)]

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CAS No.523-50-2 Angelicin

Supplier:WBV International Limited. [ China (Mainland)]

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CAS No.523-50-2 Angelicin

Supplier:Jinan Haohua Industry CO., LTD [ China (Mainland)]

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CAS No.523-50-2 Angelicin

Supplier:Shijiazhuang Xudao Chemical Co.,Ltd [ China (Mainland)]

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CAS No.523-50-2 Angelicin

Assay:>98.0% by HP...  Package:10mg; 20mg; ...

Supplier:Shanghai Forever Biotech Co., Ltd. [ China (Mainland)]

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CAS No.523-50-2 Angelicin

Assay:HPLC≥98%

Supplier:ShenZhen Sungening Bio-Tech Co.,Ltd [ China (Mainland)]

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CAS No.523-50-2 Angelicin

Supplier:Shanghai Mountain Biotech Co., Ltd. [ China (Mainland)]

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CAS No.523-50-2 Angelicin

Assay:HPLC≥98%  Appearance:powder  Package:20mg or anot...

Supplier:Gamma Technology Development Co., Ltd [ China (Mainland)]

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CAS No.523-50-2 Angelicin

Angelicin (Isopsoralen)

Supplier:WuXi AppTec (Tianjin) Co,. Ltd. [ China (Mainland)]

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CAS No.523-50-2 Angelicin

Isopsoralen HPLC≥98%

Supplier:Zhengzhou Tongguang Chemical Science C，.Ltd [ China (Mainland)]

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CAS No.523-50-2 Angelicin

Isopsoralen

Supplier:Sichuan Xianxin Biotech Co.,Ltd. [ China (Mainland)]

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CAS No.523-50-2 Angelicin

Purity ：≥98%

Supplier:Shanghai Standard Biotech Co., Ltd. [ China (Mainland)]

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CAS No.523-50-2 Angelicin

99%min

Supplier:Shanghai Yingxuan Pharmaceutical Science&Technology Co., LTD [ China (Mainland)]

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CAS No.523-50-2 Angelicin

Supplier:Shanghai Huatuo Medical Science Co., Ltd. [ China (Mainland)]

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CAS No.523-50-2 Angelicin

Supplier:Toronto Research Chemicals [ Canada]

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CAS No.523-50-2 Angelicin

Supplier:Clearsynth Labs (P) Ltd. [ India]

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CAS No.523-50-2 Angelicin

Supplier:Xi'an Aladdin Biological Technology Co.,Ltd. [ China (Mainland)]

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CAS No.523-50-2 Angelicin

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CAS No.523-50-2 Angelicin

Supplier:ZHONGSHAN PHARMCARE BIOTECH CO.,LTD [ China (Mainland)]

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Reference

Photochemically induced binding of furocoumarins with lambda phage DNA in situ
Photochemically induced binding of furocoumarins with lambda phage DNA in situ. Kittler, L.; Hradecna, Z.; Loeber, G. (Zentralinst. Mikrobiol. Exp. Ther., DAW, Jena, E. Ger.). Stud. Biophys., 66(3), 237-41 (English) 1977. CODEN: STBIBN. DOCUMENT TYPE: Journal CA Section: 3 (Biochemical Interactions) Exposure of phage l to the combined effects of UV light (365 nm) and xanthotoxin [298-81-7] or angelicin [523-50-2] decreased the rate of phage infectivity in Escherichia coli. Angelicin preferentially formed monoadducts with phage DNA, whereas xanthotoxin formed both mono- and diadducts. Photobinding of both furocoumarins had no significant effect on the adsorption of the phage particles on the surfaces of host cells.
Chromosome damage in Chinese hamster cells sensitized to near-ultraviolet light by psoralen and angelicin
Chromosome damage in Chinese hamster cells sensitized to near-ultraviolet light by psoralen and angelicin. Ashwood-Smith, M. J.; Grant, E. L.; Heddle, J. A.; Friedman, G. B. (Dep. Biol., Univ. Victoria, Victoria, B. C., Can.). Mutat. Res., 43(3), 377-85 (English) 1977. CODEN: MUREAV. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Section cross-reference(s): 8, 3, 4 The clastogenic effect of florocoumarins psoralen (I) [66-97-7] and angelicin [523-50-2] in the presence of near-UV (320-380 nm) differs greatly, as do their modes of interaction with DNA. I, which requires only 1/5 as much light energy to produce the same lethal effect as angelicin at equimolar concns., is able to cross-link DNA whereas angelicin cannot. The frequency of micronuclei which arise from chromosomal fragments shows the same differential effect as lethality. Indeed aberrations account for much or all of the lethality obsd. Metaphase anal. at comparable aberration frequencies revealed that angelicin and I both induce chromatid deletions and a wide spectrum of chromatid exchanges. These data show that both cross-links and monoadducts to the DNA can result in chromosomal aberrations. The relative contributions of cross-links and monoadducts to chromosomal aberrations still remain to be detd. It is noteworthy that extensive chromosomal damage is induced in mammalian cells by the combination of I and near-UV, a treatment which is currently widely used in the therapy of psoriasis.
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