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532-11-6

Basic Information
CAS No.: 532-11-6
Name: Anethole trithione
Article Data: 34
Molecular Structure:
Molecular Structure of 532-11-6 (Anethole trithione)
Formula: C10H8OS3
Molecular Weight: 240.371
Synonyms: 1,2-Dithiole-3-thione,5-(p-methoxyphenyl)- (6CI);3H-1,2-Dithiole-3-thione, 5-(p-methoxyphenyl)-(7CI,8CI);3-(p-Methoxyphenyl)trithione;5-(4-Methoxyphenyl)-3H-1,2-dithiole-3-thione;5-(p-Methoxyphenyl)-1,2-dithiole-3-thione;5-(p-Methoxyphenyl)-3H-1,2-dithiole-3-thione;Anethole dithiolthione;Anetholtrithion;Felviten;Heporal;Mucinol;SKF 1717;Secrebil;Sulfarlem;Sulfogal;Sulfralem;Tiopropen;Tiotrifar;Trithio;Trithio-(p-methoxyphenyl)propene;Trithioanethole;
EINECS: 208-528-5
Density: 1.41 g/cm3
Melting Point: 111°
Boiling Point: 398.1 °C at 760 mmHg
Flash Point: 194.6 °C
Appearance: Powder
PSA: 105.50000
LogP: 3.10000
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Chemistry

IUPAC Name: 5-(4-methoxyphenyl)dithiole-3-thione
CAS: 532-11-6
Molecular Formula: C10H8OS3
Molecular Weight: 240.36
EINECS: 208-528-5
Surface Tension: 68.9 dyne/cm 
Density: 1.41 g/cm3 
Flash Point: 194.6 °C 
Enthalpy of Vaporization: 62.34 kJ/mol 
Boiling Point: 398.1 °C at 760 mmHg 
Vapour Pressure: 3.46E-06 mmHg at 25°C
Molecular  structure:

Uses

Anetholtrithion (CAS NO.532-11-6) is gallbladder drugs for the treatment of cholecystitis, gallstones, acute and chronic hepatitis,and Anetholtrithion (CAS NO.532-11-6)'s also used in the treatment of dry mouth.

Toxicity Data With Reference

1.    

ims-rat LD50:35 mg/kg

    AEPPAE    Naunyn-Schmiedebergs Archiv fuer Experimentelle Pathologie und Pharmakologie. 222 (1954),244.
2.    

orl-mus LD50:3850 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),25.
3.    

ipr-mus LD50:1780 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),25.
4.    

orl-gpg LD50:6000 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),25.

 

Safety Profile

Poison by intramuscular route. Moderately toxic by ingestion and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx.

Specification

 Anetholtrithion (CAS NO.532-11-6) is also named as 5-(4-methoxyphenyl)-3h-1,2-dithiole-3-thione;5-(4-methoxyphenyl)-1,2-dithiole-3-thione;3-(p-anisy)trithione ; 3-(p-Methoxyphenyl)trithione ; 3-(p-Methoxyphenyl)-trithione ; 3H-1,2-Dithiole-3-thione,5-(p-methoxyphenyl)- ; 5-(4-methoxyphenyl)-3h-2-dithiole-3-thione and so on.