Detail of "53238-80-5"

Reference

Enzymic production of fructose-containing oligosaccharides

Enzymic production of fructose-containing oligosaccharides. (Shinohara, Satoru, Japan). Jpn. Kokai Tokkyo Koho JP 60041497 A2 5 Mar 1985 Showa, 11 pp. (Japanese). (Japan). CODEN: JKXXAF. CLASS: ICM: C12P019-18. ICI: C12P019-18, C12R001-645. APPLICATION: JP 83-148583 13 Aug 1983. DOCUMENT TYPE: Patent CA Section: 16 (Fermentation and Bioindustrial Chemistry) Fructosyltransferase [9031-67-8]-producing Aureobacidium cells are immobilized by b-1,3-1,6-glucan [53238-80-5], produced in the culture medium, and either Al2(SO4)3 or other compds., and these immobilized bacteria are used to produce inulin-type fructose-contg. oligosaccharides, composed mainly of 1-kestose [470-69-9] and nystose [13133-07-8], from sucrose [57-50-1]. The oligosaccharides are sweeteners with no unpleasant aftertaste.

Antitumor activity of cell wall b-1,3/1,6-glucans from Phytophthora species

Antitumor activity of cell wall b-1,3/1,6-glucans from Phytophthora species. Kraus, J.; Blaschek, W.; Schuetz, M.; Franz, G. (Dep. Pharm., Univ. Regensburg, Regensburg W-8400, Germany). Planta Med., 58(1), 39-42 (English) 1992.Several reagents such as 53238-80-5 is used here. CODEN: PLMEAA. ISSN: 0032-0943. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) From the cell walls of various Phytophthora species (Oomycetes) different water-sol. b-1,3/1,6-glucans were isolated and characterized. The glucans with relative mol. masses between 13 and 50 kd exhibited varying degrees of branching in the b-1,3-linked glucan backbone ranging from 14 to 50%. The dose-dependent antitumor activity of the glucans against allogeneic sarcoma-180 was investigated. It could be demonstrated that b-1,3/1,6-glucans with relative mol. masses below 50 kd can exhibit a prominent antitumor activity (inhibition rate up to 99%), being comparable to that of the high relative mol. mass (450 kd) b-1,3/1,6-glucans. Biol. activity of the glucans could be shown to be correlated with a low degree of branching. The most potent glucan with a degree of branching of 14% also was active against the syngeneic DBA/2-MC.SC-1 fibrosarcoma (inhibition rate up to 90%) and in combination with a suboptimum dose of diethylstilbestrol against Noble-Nb prostate carcinoma (inhibition rate up to 90%). .