Detail of "535-89-7"

CAS Number:
535-89-7
Name:
4-Pyrimidinamine,2-chloro-N,N,6-trimethyl-
Superlist Name:
Crimidine
Molecular Structure:
Formula:
C7H10 Cl N3
Molecular Weight:
171.65
Synonyms:
Pyrimidine,2-chloro-4-(dimethylamino)-6-methyl- (6CI,7CI,8CI);(2-Chloro-6-methylpyrimidin-4-yl)dimethylamine; 2-Chloro-4-(dimethylamino)-6-methylpyrimidine;2-Chloro-4-methyl-6-(dimethylamino)pyrimidine; Castrix; Crimidine; Crimitox;NSC 2017; W 491
EINECS:
208-622-6
Density:
1.207g/cm³
Boiling Point:
291.2°Cat760mmHg
Flash Point:
129.9°C
Hazard Symbols:
Risk Codes:
R28
Safety:
Deadly poison by ingestion and intraperitoneal routes. Can cause central nervous system damage and convulsions. Intensely poisonous to mammals. A pesticide. When heated to decomposition it emits very toxic fumes of Cl⁻ and NO_x. Details
Transport Information:
UN 2811

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Method for testing the degree of avoidance reaction in rats to acute raticides: Method for testing the degree of avoidance reaction in rats to acute raticides. K'osev, M. (MA, Sofia, Bulg.). Epidemiol., Mikrobiol. Infekts. Boles., 21(2), 48-52 (Bulgarian) 1984. CODEN: EMIBA3. ISSN: 0425-1482. DOCUMENT TYPE: Journal CA Section: 5 (Agrochemical Bioregulators) Gray rats (Rattus norvegicus) of the exptl. group were allowed to observe for 2 h the action of acute raticides on another group over wire fencing, then the fencing was removed and the exptl. group was given the bait with the same poison. The obsn. decreased the bait intake and thereby increased the survival after exposure to 3% zinc phosphide [51810-70-9], 0.5% Crimitox (castrix) [535-89-7], 0.5% Flutritex-2 (ethylenefluorohydrine) [371-62-0], and 1% Flutritex-1 (fluoracetamide) [640-19-7] from 0.21, 0.22, 0.03, and 0.03, resp., to 0.78, 0.30, 0.44, and 0.03, resp., thus showing different degrees of avoidance reaction.

The influence of crimidin metabolized by liver on brain glutamic acid decarboxylase in vitro: The influence of crimidin metabolized by liver on brain glutamic acid decarboxylase in vitro. Hansen, Kate L. (Biochem. Dep., R. Dent. Coll., Copenhagen, Den.). Acta Pharmacol. Toxicol., 39(1), 53-7 (English) 1976. CODEN: APTOA6. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) Liver homogenates were incubated with different amts. of crimidine (I) [535-89-7] for 0, 15, 30 or 45 min and the influence of their supernatants on glutamic acid decarboxylase activity of brain tissue was investigated. When 1 g of the liver homogenate was incubated with >1.17 .mu.There are some commonly used reagents with their cas registry numbers 535-89-7 and 9024-58-2 in this article.mole of I for .gtoreq.30 min, the supernatant significantly decreased the decarboxylase activity. By contrast, brain I metabolites did not inhibit the enzyme activity. .