Detail of "537-40-6"

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Quantitative analyses of methyl esters of fatty acid geometrical isomers, and of triglycerides differing in unsaturation, by the Iatroscan TLC/FID technique using silver nitrate impregnated rods

Quantitative analyses of methyl esters of fatty acid geometrical isomers, and of triglycerides differing in unsaturation, by the Iatroscan TLC/FID technique using silver nitrate impregnated rods. Sebedio, J. L.; Farquharson, T. E.; Ackman, R. G. (Stn. Rech. Qual. Aliment. Homme, INRA, Dijon 21034, Fr.). Lipids, 20(8), 555-60 (English) 1985. CODEN: LPDSAP. ISSN: 0024-4201. DOCUMENT TYPE: Journal CA Section: 17 (Food and Feed Chemistry) The relative FID responses for Iatroscan analyses of cis and trans isomers of Me esters of D6, D9 and D11 on Chromarods-S impregnated with AgNO3 were studied at load levels ranging from 0.5 to 20 mg, using Me stearate as internal std. The FID response correction factors were greater for the cis than for the trans isomers. The correction factors were relatively const. in the 10-20 mg interval, but increased in the range 0.5-5 mg. Sepn. of tristearin [555-43-1], triolein [122-32-7], trilinolein [537-40-6] and trilinolenin [14465-68-0] also was obtained on Chromarods-S impregnated with AgNO3 using a mixt. of benzene:CHCl3:AcOH (:2) as the solvent system. The relative FID responses for the triolein, trilinolein and trilinolenin were detd. at load levels ranging from 0.5 to 14.3 mg using tristearin as an internal std. The FID response correction factors of these 3 triglycerides differed significantly for load levels of 1.0, 2.5, and 5.0 mg. However, the factors could be considered as being equal in the range 10 to 14.3 mg. Correction factors were not affected by repeated re-use of the same set of Chromarods. Several hundred sepns. and scans appeared feasible.

Effect of different dietary triglycerides on 7a-hydroxylation of cholesterol and other mixed-function oxidations

Effect of different dietary triglycerides on 7a-hydroxylation of cholesterol and other mixed-function oxidations. Bjorkhem, Ingemar; Blomstrand, Rolf; Svensson, Lennart (Dep. Clin. Chem., Huddinge Univ. Hosp., Stockholm, Swed.). J. Lipid Res., 19(3), 359-69 (English) 1978. CODEN: JLPRAW. ISSN: 0022-2275. DOCUMENT TYPE: Journal CA Section: 18 (Animal Nutrition) Section cross-reference(s): 13 The effect of a diet contg. triglycerides of different fatty acid compn. on hepatic 7a-hydroxylation of cholesterol [57-88-5] was studied. 7a-Hydroxylation of exogenous and endogenous cholesterol was lower in the liver of rats fed trilinolein [537-40-6] and triolein [122-32-7] than in those fed tripalmitin [555-44-2] and trierucin [2752-99-0]. The concn. of cytochrome P-450 [9035-51-2] in liver microsomes was lower in the rats fed tripalmitin and trierucin than in those fed triolein and trilinolein. The inhibitory effect of triolein and trilinolein on 7a-hydroxylation of cholesterol and the stimulatory effect of these triglycerides on the concn. of cytochrome P-450 was not due to the small amts. of peroxides present in the unsatd. triglycerides. Thus, addn. of the antioxidant butylated hydroxyanisole [25013-16-5] did not change the general pattern with respect to 7a-hydroxylation and concn. of cytochrome P-450. However, a diet consisting of peroxidized linoleic acid further decreased 7a-hydroxylation of cholesterol. The difference between the effect obtained with triolein and trilinolein on the one hand and trierucin and tripalmitin on the other was obsd. also in expts. with lower concns. of fat in the diet and in expts. with different lighting conditions and feeding patterns. The inverse relation between cytochrome P-450 and 7a-hydroxylation of cholesterol, as well as results obtained with substrates for mixed-function oxidn. other than cholesterol suggests that most of the changes obsd. due to the different diets are specific for 7a-hydroxylation of cholesterol. The level of cholesterol 7a-hydroxylase [9037-53-0] activity was better related to the degree of absorption of fat than to the total amt. of absorbed fat or the degree of unsatn. of the fat. The results are discussed with respect to mechanisms regulating biosynthesis of bile acids.