CAS No.53823-08-8,Cascaroside A Suppliers

CAS Number:
53823-08-8
Name:
Cascaroside A
Formula:
C₂₇H₃₂O₁₄
Molecular Structure:
Synonyms:
Cascara Sagrada Barker P.E.;(10S)-1-Hydroxy-3-(hydroxymethyl)-10-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-8-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-10H-anthracen-9-one;9(10H)-Anthracenone,10-a-D-glucopyranosyl- 8-(a-D-glucopyranosyloxy)-1-hydroxy-3- (hydroxymethyl)-,(10S)-;
Molecular Weight:
580.53
Density:
1.694 g/cm³
Boiling Point:
948.1 °C at 760 mmHg
Flash Point:
315.2 °C

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Release and diffusion studies on active ingredients of anthraglycoside-containing drugs: Release and diffusion studies on active ingredients of anthraglycoside-containing drugs. Korsatko, W.; Hiermann, A. (Inst. Pharm. Chem., Karl-Franzens-Univ., Graz A-8010, Austria). Sci. Pharm., 52(2), 163-8 (German) 1984. CODEN: SCPHA4. ISSN: 0036-8709. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Infusions were prepd. from anthraglycoside-contg. plants such as Frangula, Rhamnus pushiana, Rhei, and Sennae. The contents of sennoside A [81-27-6] and sennoside B [128-57-4], glucofrangulin [18321-66-9], cascaroside A [53823-08-8], and 1,8-dihydroxyanthraquinone [117-10-2] were detd. by HPLC. The extn. times of plant materials were compared to the extn. times given in the Austrian Pharmacopeia. Max. release of the active ingredients was obsd. in the times used. An increase in the rate of diffusion of the materials was obsd. from pH 1 to 7.

HPLC analytical study of the principal constituents of cascara and frangula extracts: HPLC analytical study of the principal constituents of cascara and frangula extracts. Terracciano, M.; Gambero, P.; Percaccio, G.; Donatelli, I.; Quercia, V. (Lab. Chim. Farm., Ist. Super. Sanita, Rome, Italy). Boll. Chim. Farm., 116(7), 402-9 (Italian) 1977. CODEN: BCFAAI. ISSN: 0006-6648. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) Section cross-reference(s): 11 Rapid and specific identification and detn. of cascaroside A [53823-08-8] and cascaroside B [53861-34-0] in cascara (Rhammus purshiana) exts., and of frangulin A [521-62-0] and glucofrangulin A (I) [21133-53-9] in frangula (R. frangula) exts., was carried out by high-pressure liq. chromatog. (HPLC), using a Micropak SI-10 column and various MeOH-n-pentane mixts. as mobile phase. The amt. of cascarosides found by this technique in a dry cascara ext. was 41.7%, and a dry frangula ext. contained 2 and 15.9% frangulin A and glucofrangulin A, resp.

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