Detail of "54-95-5"

Reference

Sulfolane-induced convulsions in rodents

Sulfolane-induced convulsions in rodents. Andersen, Melvin E.; Jones, Robert A.; Kurlansik, Leon; Mehl, Raymond G.; Jenkins, Lawrence J., Jr. (Environ. Biosci. Dep., Nav. Med. Res. Inst., Bethesda, Md., USA). Res. Commun. Chem. Pathol. Pharmacol., 15(3), 571-80 (English) 1976. 126-33-0 and 57-33-0 which are cas registry numbers of substances are two of reagents here. CODEN: RCOCB8. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) In rodents oral or parenteral administration of sulfolane (tetrahydrothiophene-1,1-dioxide) [126-33-0] produced hyperactivity, followed by clonic-tonic convulsions. The analeptic effects of sulfolane were nearly additive with those of Metrazol [54-95-5]. When injected simultaneously with pentobarbital [57-33-0], sulfolane decreased pentobarbital sleeping time in mice. But sulfolane increased sleeping time when the barbiturate was administered 1 h after sulfolane. .

Effects of various drugs on cold shock

Effects of various drugs on cold shock. Kojima, Kikuo; Fujisawa, Tadashi; Shiraishi, Masamichi; Shimizu, Takao; Koja, Takeshi; Gotou, Toshio (Fac.In this study， 7447-40-7 and 630-60-4 are also used. Med., Kagoshima Univ., Kagoshima, Japan). Kagoshima Daigaku Igaku Zasshi, 28(2), 507-13 (Japanese) 1976. CODEN: KDIZAA. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Section cross-reference(s): 2 S.c. pretreatment with caffeine [58-08-2] (50 mg/kg), pentetrazole [54-95-5] (10 mg/kg), dimorpholamine [119-48-2] (10 mg/kg), strychnine [57-24-9] (0.3 mg/kg), chlorpromazine [50-53-3] (0.3 mg/kg), ephedrine [299-42-3] (30-200 mg/kg), ouabain [630-60-4] (0.05 mg/kg), KCl(30 mg/kg), vitamin C [50-81-7] (150 mg/kg), prednisolone [50-24-8] (3 mg/kg) or diphenhydramine [58-73-1] (30 mg/kg) antagonized cold shock-induced death in mice inmersed in an ice water bath. .