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540-73-8

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Basic Information
CAS No.: 540-73-8
Name: 1,2-Dimethyl hydrazine
Molecular Structure:
Molecular Structure of 540-73-8 (1,2-Dimethyl hydrazine)
Formula: C2H8 N2
Molecular Weight: 60.0989
Synonyms: 1,2-Dimethylhydrazine;DMH; Hydrazomethane; N,N'-Dimethylhydrazine; SDMH; sym-Dimethylhydrazine
Density: 0.759g/cm3
Melting Point: -8.9°C
Boiling Point: 81.5°Cat760mmHg
Flash Point: °C
Hazard Symbols: T,N
Risk Codes: R45; R23/24/25; R51/53
Safety: Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by ingestion, intraperitoneal, intravenous, subcutaneous, and intramuscular routes. Moderately toxic by inhalation. Human mutation data reported. A very dangerous fire hazard when exposed to heat, flame, or oxidizers. A high-energy propellant for liquid-fueled rockets. When heated to decomposition it emits toxic fumes of NOx.
PSA: 24.06000
LogP: 0.12200
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Chemistry

IUPAC  Name: 1,2-Dimethylhydrazine   
Molecular Formula: C2H8N2
Molecular Weight: 60.12
Freely Rotating Bonds: 1
Polar Surface Area: 6.48 Å2
Index of Refraction: 1.383
Molar Refractivity: 18.5 cm3
Molar Volume: 79.1 cm3
Polarizability: 7.33 ×10-24 cm3
Surface Tension: 20 dyne/cm
Density: 0.759 g/cm3
Enthalpy of Vaporization: 32.22 kJ/mol
Boiling Point: 81.5 °C at 760 mmHg
Vapour Pressure: 81.7 mmHg at 25°C 
The Cas Register Number of  1,2-Dimethylhydrazine is 540-73-8 .The chemical synonyms of  1,2-Dimethylhydrazine (CAS NO.540-73-8) are Hydrazine, 1,2-dimethyl-  and 1,1'-Dimethylhydrazine Dihydrochloride .The molecular structure of  1,2-Dimethylhydrazine (CAS NO.540-73-8) is.

Uses

 1,2-Dimethylhydrazine (CAS NO.540-73-8) is used in organic synthesis.

Toxicity Data With Reference

1.    

otr-hmn:fbr 230 µmol/L

    CALEDQ    Cancer Letters (Shannon, Ireland). 29 (1985),265.
2.    

dns-hmn:lng 100 µL/L

    NTIS**    National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) AD-A041-973 .
3.    

sce-mus-rec 20 mg/kg

    ENMUDM    Environmental Mutagenesis. 8 (Suppl 6)(1986),41.
4.    

hma-mus/esc 50 µmol/kg

    MUREAV    Mutation Research. 148 (1985),1.
5.    

dnd-ham:lng 2 mmol/L

    MUREAV    Mutation Research. 173 (1986),157.
6.    

sce-mus-ipr 270 µmol/kg

    TCMUD8    Teratogenesis, Carcinogenesis, and Mutagenesis. 9 (1989),219.
7.    

orl-rat LD50:100 mg/kg

    NATWAY    Naturwissenschaften. 54 (1967),285.
8.    

ihl-rat LCLo:280 ppm/4H

    AMIHAB    AMA Archives of Industrial Health. 12 (1955),609.
9.    

ipr-rat LD50:163 mg/kg

    MEPAAX    Medycyna Pracy. Industrial Medicine. 24 (1973),71.
10.    

scu-rat LD50:220 mg/kg

    XENOBH    Xenobiotica. 3 (1973),271.
11.  

Consensus Reports

IARC Cancer Review: Group 2B IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 4 ,1974,p. 145.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Poison by ingestion, intraperitoneal, intravenous, subcutaneous, and intramuscular routes. Moderately toxic by inhalation. Human mutation data reported. A very dangerous fire hazard when exposed to heat, flame, or oxidizers. A high-energy propellant for liquid-fueled rockets. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes: ToxicT,DangerousN
Risk Statements: 45-23/24/25-51/53 
R45: May cause cancer. 
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed. 
R51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 53-45-61 
S53: Avoid exposure - obtain special instructions before use. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: 2382
HazardClass: 6.1(a)
PackingGroup: I

Standards and Recommendations

DFG MAK: Animal Carcinogen, Suspected Human Carcinogen
DOT Classification:  3; Label: Flammable Liquid, Poison