Detail of "5414-21-1"

Reference

Pseudopeptides derived from neurokinins, process of preparation and pharmaceutical compositions comprising them

Pseudopeptides derived from neurokinins, process of preparation and pharmaceutical compositions comprising them. Fauchere, Jean-Luc; Kucharczyk-Gentric, Nathalie; Canet, Emmanuel; Lonchampt, Michel (Adir et Compagnie, Fr.Several substances are used for example 5414-21-1 which is its cas registry number.). Eur. Pat. Appl. EP 790254 A1 20 Aug 1997, 22 pp. DESIGNATED STATES: R: AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, NL, PT, SE. (French). (European Patent Organization). CODEN: EPXXDW. CLASS: ICM: C07K005-023. ICS: A61K038-06. APPLICATION: EP 1997-400289 10 Feb 1997.Several substances like 5414-21-1 may be metioned in this study. PRIORITY: FR 1996-1919 16 Feb 1996. DOCUMENT TYPE: Patent CA Section: 34 (Amino Acids, Peptides, and Proteins) Section cross-reference(s): 1, 63 Pseudopeptides I [R1 = indolyl, naphthyl, tetrahydronaphthyl, thienyl, substituted Ph, cycloalkyl; R2 = (un)substituted benzyl or Ph, alkyl; 1 ￡ n ￡ 8; 1 ￡ m ￡ 4] were prepd. for the use as analgesics, inflammation inhibitors, the treatment of gastrointestinal disorders, etc. Thus, [1-[4-(1H-tetrazol-5-yl)butyl]indol-3-yl]carbonyl-Hyp-Trp-OCH2C6H3(CF3) 2-3,5 K salt (Hyp = hydroxyproline) was prepd. and its biol. activity examd., e.g., its affinity for human NK1 and NK2 receptors. ..

Pseudopeptides derived from neurokinins, process of preparation and pharmaceutical compositions comprising them

Pseudopeptides derived from neurokinins, process of preparation and pharmaceutical compositions comprising them. Fauchere, Jean-Luc; Kucharczyk-Gentric, Nathalie; Canet, Emmanuel; Lonchampt, Michel (Adir et Compagnie, Fr.Several substances are used for example 5414-21-1 which is its cas registry number.). Eur. Pat. Appl. EP 790254 A1 20 Aug 1997, 22 pp. DESIGNATED STATES: R: AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LI, LU, NL, PT, SE. (French). (European Patent Organization). CODEN: EPXXDW. CLASS: ICM: C07K005-023. ICS: A61K038-06. APPLICATION: EP 1997-400289 10 Feb 1997.Several substances like 5414-21-1 may be metioned in this study. PRIORITY: FR 1996-1919 16 Feb 1996. DOCUMENT TYPE: Patent CA Section: 34 (Amino Acids, Peptides, and Proteins) Section cross-reference(s): 1, 63 Pseudopeptides I [R1 = indolyl, naphthyl, tetrahydronaphthyl, thienyl, substituted Ph, cycloalkyl; R2 = (un)substituted benzyl or Ph, alkyl; 1 ￡ n ￡ 8; 1 ￡ m ￡ 4] were prepd. for the use as analgesics, inflammation inhibitors, the treatment of gastrointestinal disorders, etc. Thus, [1-[4-(1H-tetrazol-5-yl)butyl]indol-3-yl]carbonyl-Hyp-Trp-OCH2C6H3(CF3) 2-3,5 K salt (Hyp = hydroxyproline) was prepd. and its biol. activity examd., e.g., its affinity for human NK1 and NK2 receptors. ..