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54597-56-7

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Basic Information
CAS No.: 54597-56-7
Name: Monomycin
Molecular Structure:
Molecular Structure of 54597-56-7 (Monomycin)
Formula: N/A
Safety: Poison by intravenous route. Moderately toxic by intraperitoneal and subcutaneous routes.
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Chemistry

Product Name: Monomycin
CAS NO:54597-56-7
Classification Code : Drug / Therapeutic Agent ;Natural Product

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo subcutaneous 600mg/kg (600mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ATAXIA

GASTROINTESTINAL: NAUSEA OR VOMITING		 Antibiotiki. Vol. 5(4), Pg. 10, 1960.
mouse LD oral > 2gm/kg (2000mg/kg)   Antibiotiki. Vol. 5(4), Pg. 10, 1960.
mouse LD50 intraperitoneal 510mg/kg (510mg/kg)   "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds., Tokyo, Univ. of Tokyo Press, 1967Vol. -, Pg. 433, 1967.
mouse LD50 intravenous 77mg/kg (77mg/kg)   Archivum Immunologiae et Therapiae Experimentalis. Vol. 10, Pg. 947, 1962.
mouse LD50 subcutaneous 615mg/kg (615mg/kg)   "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds., Tokyo, Univ. of Tokyo Press, 1967Vol. -, Pg. 433, 1967.
rabbit LDLo intravenous 250mg/kg (250mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITH APPROPRIATE ANESTHESIA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA		 Antibiotiki. Vol. 5(4), Pg

Safety Profile

Poison by intravenous route. Monomycin (CAS NO:54597-56-7) is moderately toxic by intraperitoneal and subcutaneous routes.