CAS No.5466-88-6,2H-1,4-Benzoxazin-3(4H)-one Suppliers,MSDS download

Detail of "5466-88-6"

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CAS Number:

5466-88-6

Name:

2H-1,4-Benzoxazin-3(4H)-one

Molecular Structure:

Formula:

C₈H₇NO₂

Molecular Weight:

149.15

Synonyms:

2,3-Dihydro-3-oxo-4H-1,4-benzoxazine;2H-1,4-Benzoxazin-3-one;2H-Benzo[b][1,4]oxazin-3(4H)-one;3,4-Dihydro-1,4-benzoxazin-3(2H)-one;3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine;4H-Benzo[1,4]oxazin-3-one;NSC 26354;

Density:

1.245 g/cm³

Melting Point:

172-176 °C

Boiling Point:

337.728 °C at 760 mmHg

Flash Point:

158.052 °C

Appearance:

white to almost white crystalline powder

Hazard Symbols:

Risk Codes:

36/37/38

Safety:

26-36-37/39 Details

Reference

Synthesis and biological activity of some substituted 4H-[1,2,4]-triazino[3,4-c][1,4]-benzoxazin-5-ones and 4H-[1,2,4]-triazino-[3,4-c][1,4]-benzothiazin-5-ones: Synthesis and biological activity of some substituted 4H-[1,2,4]-triazino[3,4-c][1,4]-benzoxazin-5-ones and 4H-[1,2,4]-triazino-[3,4-c][1,4]-benzothiazin-5-ones. Sastry, C. V. Reddy; Rao, K. Srinivasa; Jain, M. L. (IDPL Res. Cent., Indian Drugs and Pharm. Ltd., Hyderabad 500 037, India). Indian J.In this article, certain chemicals are used. Some of their cas registry numbers are 5466-88-6 and 27320-99-6 Pharm. Sci., 53(4), 180-3 (English) 1991. CODEN: IJSIDW. ISSN: 0250-474X. DOCUMENT TYPE: Journal CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Section cross-reference(s): 1 Title compds. I (R = H, R1 = H, Me, X = O; R = 8-Me, 9-Me, 8-Cl, 8-NO2, 9-NO2, R1 = H, X = O; R = H, R1 = H, Me, X = S; R = 9-Me, 9-NO2, R1 = H, X = S) were prepd. and evaluated for antiinflammatory activity. Thus, alkylation of benzoxazinone or -thiazinone II (R2 = H) with BrCH2CO2Et gave II (R2 = CH2CO2Et) (III). III reacted with Lawesson's reagent and cyclized with H2NNH2 to give I. I (R = 8-Me, R1 = H, X = O; R = H, R1 = Me, X = S) had moderate antiinflammatory activity. .

Lipophilicity studies on b-blocker benzoxazinone derivatives: Lipophilicity studies on b-blocker benzoxazinone derivatives. Panderi, Irene; Angelopoulos, Christos; Tsantili-Kakoulidou, Anna; Kazanis, Michael; Vavayannis, Andreas (Department of Pharmacy, Division of Pharmaceutical Chemistry, University of Athens, Athens 15771, Greece). Farmaco, 52(3), 167-172 (English) 1997 Societa Chimica Italiana.In this study，5466-88-6 is also used. CODEN: FRMCE8. ISSN: 0014-827X. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Section cross-reference(s): 22 An investigation into the lipophilicity of a series of b-blocker benzoxazinone derivs. was carried out. Octanol-water partition coeffs. were detd. and correlated with calcd. values according to the systems of Rekker, Leo-Hansch, Ghose-Crippen and Suzuki-Kudo. Derivations are discussed. Partition coeffs. were also correlated with chromatog. indexes (RMW), obtained under different conditions concerning the stationary and mobile phase. Differences in the lipophilic behavior obsd. among the systems were examd. in detail. Moreover, distribution coeffs. at pH 7.4 have been detd.Some chemicals with cas registry numbers like 5466-88-6 are also used. and compared to corresponding apparent RMW values. ..

Detail of "5466-88-6"

2H-1,4-Benzoxazin-3(4H)-one

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CAS No.5466-88-6 2H-1,4-Benzoxazin-3(4H)-one

CAS No.5466-88-6 2H-1,4-Benzoxazin-3(4H)-one

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CAS No.5466-88-6 2H-1,4-Benzoxazin-3(4H)-one

CAS No.5466-88-6 2H-1,4-Benzoxazin-3(4H)-one

CAS No.5466-88-6 2H-1,4-Benzoxazin-3(4H)-one

CAS No.5466-88-6 2H-1,4-Benzoxazin-3(4H)-one

CAS No.5466-88-6 2H-1,4-Benzoxazin-3(4H)-one

CAS No.5466-88-6 2H-1,4-Benzoxazin-3(4H)-one

CAS No.5466-88-6 2H-1,4-Benzoxazin-3(4H)-one

CAS No.5466-88-6 2H-1,4-Benzoxazin-3(4H)-one

CAS No.5466-88-6 2H-1,4-Benzoxazin-3(4H)-one

CAS No.5466-88-6 2H-1,4-Benzoxazin-3(4H)-one

CAS No.5466-88-6 2H-1,4-Benzoxazin-3(4H)-one

CAS No.5466-88-6 2H-1,4-Benzoxazin-3(4H)-one

Reference