Reference

Specificity of the disaccharide effect in the rat

Specificity of the disaccharide effect in the rat. Michaelis, O. E., IV; Szepesi, B. (Nutr. Inst., ARS, Beltsville, Md., USA). Nutr. Metab., 21(6), 329-40 (English) 1977. CODEN: NUMEBI. DOCUMENT TYPE: Journal CA Section: 18 (Animal Nutrition) Male rats were starved and refed diets contg. 40% disaccharides (maltose [69-79-4], trehalose [99-20-7], sucrose [57-50-1], turanose [547-25-1]), trisaccharide (melezitose [597-12-6]), starch [9005-25-8], or the monosaccharide equivalents. Responses of hepatic glucose-6-phosphate dehydrogenase (G6PD) [9001-40-5] malic enzyme (ME) [9028-47-1], fatty acid synthetase (FAS) [9045-77-6], and total liver lipid (TLL) or changes in concn. of portal blood total carbohydrate and fructose [57-48-7] were detd. folowing refeeding of the different carbohydrate diets. Maltose, trehalose, sucrose, and turanose refeeding resulted in G6PD and ME responses which were higher than the responses to their component monosaccharides (disaccharide effect). Starch refeeding decreased the responses of G6PD, ME, and FAS when compared to refeeding of glucose. Refeeding diets contg. fructose (sucrose, turanose, melezitose, and monosaccharide equivalents contg. fructose) increased the responses of G6PD, ME, FAS, and TLL. No correlation between portal blood carbohydrate concn. and hepatic enzyme levels could be demonstrated. Evidently, readily digestible disaccharides produce an effect which is greater than the effect produced by their monosaccharide equivalents. If these disaccharide configurations are fed as part of a trisaccharide or polysaccharide, the disaccharide effect is no longer discernible.

Stepwise screening of sugar substitutes - prescreening with enzymes

Stepwise screening of sugar substitutes - prescreening with enzymes. 1. a-Glucosidase from yeast. Siebert, G.; Ziesenitz, S. C. (Abt. Exp. 20942-99-8 and 547-25-1 are cas registry numbers. These chemicals are also mentioned in this article. Zahnheilkd., Univ. Wuerzburg, Wuerzburg D-8700, Fed. Rep. Ger.). Z. Ernaehrungswiss., 25(4), 242-7 (German) 1986. CODEN: ZERNAL. ISSN: 0044-264X. DOCUMENT TYPE: Journal CA Section: 17 (Food and Feed Chemistry) Section cross-reference(s): 7 Michaelis consts. and max. velocities were found for yeast glucosidase [9033-06-1] with a variety of glucosylglucose and disaccharide alcs. The type of glycosidic bond in the substrate was more important for enzyme behavior than was redn. of the carbonyl group. The enzyme is suitable for testing the cariogenicity and caloric content of sugar substituents contg. saccharide residues. .