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Detail of "55268-74-1"

  • MSDS Download
  • CAS Number:
  • 55268-74-1
  • Name:
  • Praziquantel

  • Molecular Structure:
  • Formula:
  • C19H24N2O2
  • Molecular Weight:
  • 312.45
  • Synonyms:
  • Drontal;Prestwick_402;4H-Pyrazino(2,1-a)isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-;Biltricide (TN);2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one;5-24-03-00361 (Beilstein Handbook Reference);2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro- 4H-pyrazino[2,1-a]-isoquinolin-4-one;Drontal Plus;Droncit;Praziquantel (JAN/USP);Cutter;
  • EINECS:
  • 259-559-6
  • Density:
  • 1.22 g/cm3
  • Melting Point:
  • 136-138 °C
  • Boiling Point:
  • 544.1 °C at 760 mmHg
  • Flash Point:
  • 254.6 °C
  • Hazard Symbols:
  • FlammableF,CorrosiveC
  • Risk Codes:
  • 11-34
  • Safety:
  • 16-26-36/37/39-45 Details

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CAS No.55268-74-1 PraziquantelCompetitive Product

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Assay:more than 97...  Appearance:White or alm...  Package:20kg/ Plasti...Storage:Kept air tig...

praziquantel C19H24N2O2

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Praziquantel Standard: USP31 GMP Certificates DMF Open parts Specifications: 2) Identification: positive reaction 3) Melting point: 136 ~ 142oC 4) Loss on drying: 0.5% max. 5) Residue on ignition: 0.1% max. 6) Phosphate: 0.05% max. 7) Heavy metals: 20ppm max. 8)

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Praziquatel Standard : USP30 Melting Poind:136.0-142.0℃ Loss on drying:0.5%max residue on ignition:0.1%max Heavy metal:20ppm max Phosphate:0.05%max Residual solvents Chloroform:60ppm max Acetone:5000ppm max Related Compounds A:0.2% max B:0.2% max

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Item name: Praziquantel CAS: 55268-74-1 Molecular formula:C19H24N2O2 Molecular weight: 312.41 Shipment: general chemical Dear sirs, we can supply you Praziquantel, if you are interested, kind please feel free contact us and we will send you the best price, thank you very m

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CAS No.55268-74-1 Praziquantel

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Chemical Name: 2-Cyclohexylcarbonyl-1,2,3,6,7,11b-hexahydro-4H-pyrazino Structural Formula: Molecular Formula: C19H24N2O2 Molecular Weight: 312.41

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CAS No.55268-74-1 Praziquantel

Praziquantel is a synthetic anthelmintic agent that can be used for such diseases : 1.Schistosoma , which is effective is single dose since 2005 . 2.It is used against liver flukes such as Clonorchis sinensis, Travelers . 3.It is also used to treat Intestinal tapeworms.

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Reference

Mutagenicity studies with praziquantel, a new anthelmintic drug: tissue-, host-, and urine-mediated mutagenicity assays
Mutagenicity studies with praziquantel, a new anthelmintic drug: tissue-, host-, and urine-mediated mutagenicity assays. Obermeier, J.; Frohberg, H. (Inst. Toxicol., E. Merck, Darmstadt, Ger.). Arch. Toxicol., 38, 149-61 (English) 1977. CODEN: ATXKA8. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Praziquantel, (I) [55268-74-1] a new anthelmintic with activity against all species of schistosomes pathogenic to man, and against a wide range of cestodes, was tested for mutagenic potential. For the detection of both base substitutions and frameshift mutations, Salmonella typhimurium TA 100 and TA 98 were used as test strains. Using the plate assay with and without added S-9, host-mediated assay, and urine-mediated assay without and after incubation with b-glucuronidase/arylsulfatase, no mutagenic activity could be detected.
Mutagenicity studies with praziquantel, a new anthelmintic drug, in mammalian systems
Mutagenicity studies with praziquantel, a new anthelmintic drug, in mammalian systems. Machemer, L.; Lorke, D. (Inst. Toxikol., Bayer A.-G., Wuppertal-Elberfeld, Ger.). Arch. Toxicol., 39(2), 187-97 (English) 1978. CODEN: ATXKA8. ISSN: 0003-9446. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) No sign of a mutagenic action of praziquantel (I) [55268-74-1] was found in various in vivo test systems covering both somatic cells (erythroblasts of the bone marrow of the mouse) and germ cells (all spermatogenetic stages in the mouse, preovulatory oocytes of the mouse, and spermatogonia of the Chinese hamster).
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