Reference

Facile unmasking of ethenylated isocytosines via diacetoxylation with lead tetraacetate

Facile unmasking of ethenylated isocytosines via diacetoxylation with lead tetraacetate. Sako, Magoichi; Totani, Reiko; Hirota, Kosaku; Maki, Yoshifumi (Gifu Pharm. Univ., Gifu 502, Japan). Chem. Pharm. Bull., 40(1), 235-7 (English) 1992. 621-62-5 and 140685-72-9 are cas registry numbers of chemicals which are used as reagents here. CODEN: CPBTAL. ISSN: 0009-2363. DOCUMENT TYPE: Journal CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Treatment of ethenylated isocytosines, imidazolo[1,2-a]pyrimidine-5(1H)-one (I) and -7(8H)-one (II), with lead tetraacetate (LTA) in glacial acetic acid followed by alk. hydrolysis resulted in the smooth removal of the ethenyl group to give isocytosine (III) in high yields. The unmasking of I by LTA to III was compared with the results using iodosylbenzene diacetate and N-bromosuccinimide. .