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55779-06-1

Basic Information
CAS No.: 55779-06-1
Name: FORTIMICIN
Article Data: 7
Molecular Structure:
Molecular Structure of 55779-06-1 (FORTIMICIN)
Formula: C17H35 N5 O6
Molecular Weight: 405.495
Synonyms: L-chiro-Inositol,4-amino-1-[(aminoacetyl)methylamino]-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-b-L-lyxo-heptopyranosyl)-6-O-methyl-(9CI); Antibiotic KW 1070; Astromicin; Fortimicin A; KW 1070
Density: 1.31g/cm3
Melting Point: >200° (dec)
Boiling Point: 621.1°Cat760mmHg
Flash Point: 329.4°C
Safety: Poison by subcutaneous and intravenous routes. Moderately toxic by intraperitoneal and intramuscular routes. Mildly toxic by ingestion. Experimental teratogenic and reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
PSA: 192.54000
LogP: -0.78420
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Chemistry

Product Name: Fortimicin a
Synonyms of Fortimicin a (CAS NO.55779-06-1): Antibiotic KW-1070 ; Astromicin ; Astromicina ; Astromicina [INN-Spanish] ; Astromicine ; Astromicine [INN-French] ; Astromicinum ; Astromicinum [INN-Latin] ; KW 1070 ; KW-1070 ; UNII-7JHD84H15J ; XK 70-1 ; XK-70-1 ; 4-Amino-1-((aminoacetyl)methylamino)-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-6-O-methyl-L-chiro-inositol ; L-chiro-Inositol, 4-amino-1-((aminoacetyl)methylamino)-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-6-O-methyl- ;
CAS NO: 55779-06-1
Molecular Formula Fortimicin a (CAS NO.55779-06-1): C17H35N5O6 
Molecular Weight: 405.4897  
H bond acceptors: 11
H bond donors: 10
Freely Rotating Bonds: 12
Polar Surface Area: 192.54 Å2
Index of Refraction: 1.585
Molar Refractivity: 103.23 cm3
Molar Volume: 307.9 cm3
Surface Tension: 65.8 dyne/cm
Density: 1.31 g/cm3
Flash Point: 329.4 °C
Enthalpy of Vaporization: 105.51 kJ/mol
Boiling Point: 621.1 °C at 760 mmHg
Vapour Pressure: 5.01E-18 mmHg at 25°C
Molecular Structure:

Uses

 Fortimicin a (CAS NO.55779-06-1) is used as aminoglycoside antibiotics, broad spectrum of gram-negative bacilli .

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 97mg/kg (97mg/kg)   Antimicrobial Agents and Chemotherapy. Vol. 29, Pg. 543, 1986.

Safety Profile

Poison by subcutaneous and intravenous routes. Moderately toxic by intraperitoneal and intramuscular routes. Mildly toxic by ingestion. Experimental teratogenic and reproductive effects. When heated to decomposition it emits toxic fumes of NOx.