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Detail of "5636-83-9"

  • CAS Number:
  • 5636-83-9
  • Name:

  • Dimetindene

  • Molecular Structure:
  • Formula:
  • C20H24N2
  • Molecular Weight:
  • 292.42
  • Synonyms:
  • 1H-Indene-2-ethanamine, N,N-dimethyl-3-(1-(2-pyridinyl)ethyl)-, (Z)-2-butenedioate (1:1);SU 6518;3614-69-5;1H-Indene-2-ethanamine,N,N-dimethyl-3- [1-(2-pyridinyl)ethyl]-;5-22-11-00123 (Beilstein Handbook Reference);1H-Indene-2-ethanamine, N,N-dimethyl-3-(1-(2-pyridinyl)ethyl)- (9CI);Pyridine, 2-(1-(2-(2-(dimethylamino)ethyl)inden-3-yl)ethyl)-, maleate (1:1);Dimethindene maleate [USAN];N-(4-iodophenyl)-1-[4-(thietan-3-yloxy)phenyl]methanimine;Dimetindeno [INN-Spanish];Pyridine, 2-(1-(2-(2-(dimethylamino)ethyl)inden-3-yl)ethyl)-;Dimetindenum [INN-Latin];Forhistal;but-2-enedioic acid; N,N-dimethyl-2-[1-(1-pyridin-2-ylethyl)-3H-inden-2-yl]ethanamine;Dimethindene maleate;Dimethyl{2-[3-(2-pyridylethyl)inden-2-yl]ethyl}amine;2-(1-(2-(2-(Dimethylamino)ethyl)inden-3-yl)ethyl)pyridine maleate (1:1);N,N-Dimethyl-N-(3-(1-(2-pyridyl)ethyl)-2-indenylethyl)amin;2-(1-(2-(2-(Dimethylamino)ethyl)inden-3-yl)ethyl)pyridine maleate;N,N-dimethyl-2-[1-(1-pyridin-2-ylethyl)-3H-inden-2-yl]ethanamine;Forhistal maleate;Fenistil;2-(1-(2-(2-Dimethylaminoethyl)inden-3-yl)ethyl)pyridine;N,N-Dimethyl-3-(1-(2-pyridyl)ethyl)inden-2-ethylamin;Dimethpyrindene;Dimetindene hydrogen maleate;Antihistamine compound;Dimethpyrindene maleate;SU-6518;
  • EINECS:
  • 227-083-8
  • Density:
  • 1.065 g/cm3
  • Boiling Point:
  • 416.3 °C at 760 mmHg
  • Flash Point:
  • 205.6 °C
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CAS No.5636-83-9 Dimetindene

Supplier:Shanghai Fuhe Chemistry Technology Co.,Ltd. [ China (Mainland)]

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Address:Shanghai Fuhe Chemistry Technology Co.,Ltd.

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CAS No.5636-83-9 Dimetindene

Supplier:Shaanxi TOP Pharm Chemical Co., Ltd. [ China (Mainland)]

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Address:RM.11704 zizhu building, No. 108 west sector, south er huan, Xi'an China

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CAS No.5636-83-9 Dimetindene

Supplier:AlliChem, LLC [ United States]

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Tel:(410)633-1363.

Address:Allichem LLC, 6411 Beckley Street, Suite N215, Baltimore, Maryland 21224,

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CAS No.5636-83-9 Dimetindene

Supplier:Shanghai Custom Chemicals Corporation [ China (Mainland)]

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Tel:86-21-61556465

Address:Room 1919,building 3,No.277 Zheqiao Road,Pudong New District,Shanghai

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Reference

Anaphylactoid reactions following administration of plasma substitutes in man
Anaphylactoid reactions following administration of plasma substitutes in man. Prevention of this side-effect of haemaccel by premedication with H1- and H2-receptor antagonists. Lorenz, W.; Doenicke, A.; Dittmann, I.; Hug, P.; Schwarz, B. (Abt. Exp. Chir. Pathol. Biochem., Univ. Marburg, Marburg, Ger.). Anaesthesist, 26(12), 644-8 (German) 1977. CODEN: ANATAE. ISSN: 0003-2417. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) In human subjects, the anaphylactic and allergic reactions following Haemaccel [8057-73-6] infusion were prevented by pretreatment with a combination of dimethpyrindene [5636-83-9] (0.1 mg/kg) and cimetidine [51481-61-9] (10 mg/kg).
Drug transport by lipophilic polymer membranes
Drug transport by lipophilic polymer membranes. 2. Effect of partition and diffusion coefficients. Lippold, Barbel H.; Lichey, Johann F. (Inst. Pharm. Technol., Univ. Duesseldorf, Duesseldorf D-4000/1, Fed. Rep. Ger.). Acta Pharm. Technol., 30(2), 140-54 (German) 1984. CODEN: APTEDD. ISSN: 0340-3157. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) The diffusion coeffs. Dv of dimetindene [5636-83-9] and salicylamide [65-45-2] in polymer membranes were calcd. from the corresponding membrane-water partition coeffs. and permeability consts. The Dv values were compared with the diffusion coeffs., DL and DF, obtained from the lag times of the membrane permeation processes and the release rates, resp. Only the DL and DF valves agreed. The DF in the polymer membrane for both drugs was in the order: polydimethyl siloxane > ethylene-Et acrylate copolymer [9010-86-0] > ethylene-vinyl acetate copolymer [24937-78-8], polyamide 6 [25038-54-4] and polyamide 66 [32131-17-2] > cellulose triacetate [9012-09-3] > polyamide 610 [9008-66-6] > PVC [9002-86-2] > polypropylene [9003-07-0]. The variation of the diffusion coeffs. was more pronounced than the variation of the resp. paraffin coeffs. The diffusion coeffs. within the polymer are related to the mol. wt. of the drug.
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