Detail of "56678-09-2"

CAS Number:
56678-09-2
Name:
1(2H)-Anthracenone,7-[(1R,3S)-3,4-dihydro-10-hydroxy-7,9-dimethoxy-1,3-dimethyl-1H-naphtho[2,3-c]pyran-5-yl]-3,4-dihydro-3,8,9-trihydroxy-3-methyl-,(7S)- (9CI)
Molecular Structure:
Formula:
C32H32 O8
Molecular Weight:
0
Synonyms:
1H-Naphtho[2,3-c]pyran,1(2H)-anthracenone deriv.; T 544; Toxin T 544; Tullidinol

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Buckthorn neuropathy: effects of intraneural injection of Karwinskia humboldtiana toxins: Buckthorn neuropathy: effects of intraneural injection of Karwinskia humboldtiana toxins. Mitchell, J.; Weller, R. O.; Evans, H.; Arai, I.; Daves, G. D., Jr. (Dep. Pathol., Southampton Univ. Hosp., Southampton, Engl.). Neuropathol. Appl. Neurobiol., 4(2), 85-97 (English) 1978. CODEN: NANEDL. ISSN: 0305-1846. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) Toxins 496 (I) [56709-26-3] and T544 (II) [56678-09-2] were isolated from dried K. humboldtiana fruit, and injected in sesame oil into the rat sciatic nerve. Within 3-4 days, oil droplets which probably contained the toxins were obsd. in cytoplasm of Schwann cells with intact myelin sheaths, and at 5-6 days flaccid paresis in the limbs occurred along with segmental demyclination of the larger nerve fibers. Max. paresis was obsd. by day 10-20 depending on dose. I produced more severe paresis than comparable doses of II. The findings suggest that the I and II have a primary action on Schwann cell metab.