CAS No.57-39-6,Tris(2-methyl-1-aziridinyl)phosphine oxide Suppliers

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Basic Information

Molecular Structure:
CAS No.:	57-39-6
Name:	Tris(2-methyl-1-aziridinyl)phosphine oxide
Article Data:	2

Formula:	C₉H₁₈N₃OP
Molecular Weight:	215.235
Synonyms:	Phosphineoxide, tris(2-methyl-1-aziridinyl)- (6CI,8CI);EMT 50003;MAPO;MAPO(chemosterilant);Metapa;Metapoxide;Metepa;Methaphoxide;Methyl aphoxide;NSC 54054;Trimethylaziridinylphosphine oxide;Tris(1,2-propylene)phosphoramide;Tris(2-methylaziridinyl)phosphine oxide;Tris(methylaziridinyl)phosphine oxide;
EINECS:	200-326-5
Density:	1.275 g/cm³
Melting Point:	25°C
Boiling Point:	311.678 °C at 760 mmHg
Flash Point:	142.298 °C
Appearance:	Water white to straw coloured viscous liquid
Hazard Symbols:	Xi
Risk Codes:	R38
Transport Information:	UN 2810
PSA:	35.91000
LogP:	1.02050

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Chemistry

IUPAC Name: 1-Bis(2-methylaziridin-1-yl)phosphoryl-2-methylaziridine
The MF of 1-Bis(2-methylaziridin-1-yl)phosphoryl-2-methylaziridine (57-39-6) is C₉H₁₈N₃OP.

The MW of 1-Bis(2-methylaziridin-1-yl)phosphoryl-2-methylaziridine (57-39-6) is 215.23.
Synonyms of 1-Bis(2-methylaziridin-1-yl)phosphoryl-2-methylaziridine (57-39-6): 1,1',1'-Phosphinylidynetris(2-methyl)azridine ; 1,1',1'-Phosphinylidynetris(2-methyl-aziridine ; 1,1',1'-Phosphinylidynetris[2-methyl-aziridin]
Appearance: White to straw colored liquid with a strong ammonia-like odor
Index of Refraction: 1.576
EINECS: 200-326-5
Density: 1.27 g/ml
Flash Point: 142.3 °C
Boiling Point: 311.7 °C

Uses

1-Bis(2-methylaziridin-1-yl)phosphoryl-2-methylaziridine (57-39-6) is used in the manufacture of composite solid propellant and the coated layer.

Toxicity Data With Reference

1.	dni-esc 10 mmol/L	IJEBA6 Indian Journal of Experimental Biology. 22 (1984),453.
2.	cyt-hmn:lym 20 mg/L	SOGEBZ Soviet Genetics. Translation of GNKAA5. 8 (1972),783.
3.	orl-rat LD50:136 mg/kg	TXAPA9 Toxicology and Applied Pharmacology. 14 (1969),515.
4.	skn-rat LD50:183 mg/kg	BWHOA6 Bulletin of the World Health Organization. 31 (1964),737.
5.	orl-mus LD50:292 mg/kg	INHEAO Industrial Health. 8 (1970),54.
6.	skn-mus LD50:375 mg/kg	INHEAO Industrial Health. 8 (1970),54.
7.	ipr-mus LDLo:3125 µg/kg	TXAPA9 Toxicology and Applied Pharmacology. 23 (1972),288.
8.	scu-mus LD50:140 mg/kg	INHEAO Industrial Health. 8 (1970),54.
9.	orl-ckn LD50:329 mg/kg	TXAPA9 Toxicology and Applied Pharmacology. 16 (1970),100.
10.	orl-dom LDLo:50 mg/kg	ANYAA9 Annals of the New York Academy of Sciences. 111 (1964),715.

Consensus Reports

IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 9 ,1975,p. 107.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

Safety Profile

Poison by ingestion, skin contact, intraperitoneal, and subcutaneous routes. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental carcinogenic data. Animal experiments suggest cholinesterase inhibition, possibly due to metabolic products of this material in the body. When heated to decomposition it emits very toxic fumes of NO_x and PO_x.
Safety information of 1-Bis(2-methylaziridin-1-yl)phosphoryl-2-methylaziridine (57-39-6):
RIDADR 2810
HazardClass 6.1(b)
PackingGroup III