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571188-59-5

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Basic Information
CAS No.: 571188-59-5
Name: OTAVA-BB 1207229
Article Data: 76
Molecular Structure:
Molecular Structure of 571188-59-5 (OTAVA-BB 1207229)
Formula: C14H22N4O2
Molecular Weight: 278.354
Synonyms: tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate;
Density: 1.182g/cm3
Melting Point: 130-132℃
Boiling Point: 454.066oC at 760 mmHg
Flash Point: 228.411oC
PSA: 71.69000
LogP: 2.30500
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Synthetic route
571189-16-7

4-(6-nitropyridin-3-yl)-piperazine-1-carboxylic acid tert-butyl ester

571188-59-5

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethanol; water for 2h;100%
With palladium on activated charcoal; hydrogen In ethanol for 3h;100%
With palladium 10% on activated carbon; hydrogen In methanol at 25℃; under 2250.23 Torr; for 4h; Autoclave;99.1%

1-(5-nitro-2Z,4Z-pentadienenitrile-4-yl)-4-tert-butoxycarbonylpiperazine

571188-59-5

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

Conditions
ConditionsYield
With 5%-palladium/activated carbon; hydrogen; ammonium chloride In methanol at 40 - 45℃; under 1500.15 - 2250.23 Torr; Temperature; Reagent/catalyst; Pressure; Solvent; Autoclave;95.3%
504-29-0

2-aminopyridine

57260-71-6

1-t-Butoxycarbonylpiperazine

571188-59-5

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

Conditions
ConditionsYield
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen In 1,2-dichloro-ethane for 10h; Reagent/catalyst; Irradiation;95%
24424-99-5

di-tert-butyl dicarbonate

5-(piperazin-1-yl)pyridin-2-amine

571188-59-5

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

Conditions
ConditionsYield
In methanol; water at 20℃; Solvent; Inert atmosphere;94%
20511-12-0

2-amino-5-iodopyridine

57260-71-6

1-t-Butoxycarbonylpiperazine

571188-59-5

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

Conditions
ConditionsYield
With potassium phosphate; copper(l) iodide; ethylene glycol In isopropyl alcohol at 110℃; for 10h; Ullmann Condensation; Sealed tube;85%
775288-71-6

1-(6-nitropyridin-3-yl)piperazine

571188-59-5

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 190.93 g / aq. NaHCO3 / tetrahydrofuran / 3 h
2: 83 percent / H2 / Raney Nickel / methanol / 5 h / 2585.74 Torr
View Scheme
Multi-step reaction with 2 steps
1: triethylamine / tetrahydrofuran / 50 °C
2: 10% palladium on activated carbon; hydrogen / methanol
View Scheme
Multi-step reaction with 2 steps
1: sodium hydrogencarbonate / water; tetrahydrofuran / 3 h / 20 °C
2: hydrogen / water; methanol / 5 h / 2585.81 Torr
View Scheme
Multi-step reaction with 2 steps
1: dmap; triethylamine / dichloromethane / 8 h / 20 °C
2: hydrogen; palladium 10% on activated carbon / methanol / 20 °C
View Scheme
39856-50-3

5-bromo2-nitropyridine

571188-59-5

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: tetra-n-butylammonium iodide; K2CO3 / dimethylsulfoxide / 80 - 100 °C
2: 190.93 g / aq. NaHCO3 / tetrahydrofuran / 3 h
3: 83 percent / H2 / Raney Nickel / methanol / 5 h / 2585.74 Torr
View Scheme
Multi-step reaction with 3 steps
1: tetra-(n-butyl)ammonium iodide; potassium carbonate / dimethyl sulfoxide / 80 °C
2: triethylamine / tetrahydrofuran / 50 °C
3: 10% palladium on activated carbon; hydrogen / methanol
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / dimethyl sulfoxide / 65 °C
2: hydrogen / palladium 10% on activated carbon / ethanol / 16 h / 20 °C / Inert atmosphere
View Scheme
571189-16-7

4-(6-nitropyridin-3-yl)-piperazine-1-carboxylic acid tert-butyl ester

aluminum nickel

571188-59-5

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

Conditions
ConditionsYield
In methanol; n-heptane; water; hydrogen
57260-71-6

1-t-Butoxycarbonylpiperazine

571188-59-5

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium carbonate / dimethyl sulfoxide / 65 °C
2: hydrogen / palladium 10% on activated carbon / ethanol / 16 h / 20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / dimethyl sulfoxide / 65 °C
2: palladium 10% on activated carbon; hydrogen / ethanol / 16 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: 1-methyl-pyrrolidin-2-one / 3 h / 120 °C
2: hydrogen; palladium 10% on activated carbon / ethanol / 2 h
View Scheme
24424-99-5

di-tert-butyl dicarbonate

571188-59-5

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium carbonate / water; tetrahydrofuran / 1.5 h / 5 - 28 °C / Inert atmosphere
2: hydrogen / palladium 10% on activated carbon / water; methanol / 0.25 h / 19 - 54 °C / 1551.49 - 2327.23 Torr / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: N,N-dimethyl-formamide
2: hydrogen; palladium 10% on activated carbon / methanol
View Scheme
Multi-step reaction with 2 steps
1.1: N,N-dimethyl-formamide; isopropyl alcohol / 20 - 60 °C
1.2: 20 °C
2.1: zinc; acetic acid / water / 2 h / 10 - 20 °C
View Scheme
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  • 1-Boc-4-(6-Aminopyridin-3-Yl)Piperazine

  • Casno:

    571188-59-5

    1-Boc-4-(6-Aminopyridin-3-Yl)Piperazine

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    Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By

    Triumph International Development Limilted is engaged in the API, pharmaceutical intermediates research and developmen.Adhering to the "customer first" business philosophy,we suppl

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    China (Mainland)  |  Contact Details

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  • 4-(6-Aminopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester

  • Casno:

    571188-59-5

    4-(6-Aminopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0

    4-(6-Aminopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester is one of the most competitive products in our company, we can supply it with good quality and best price. Appearance:White to yellow solid Storage:Room temperature, Keep in Dark Pl

    Nanjing Fred Technology Co.,Ltd. is a Fine Chemicals Company, specializing in research, development, manufacture and distribute raw materials for pharmaceutical, healthcare, bioc

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    Business Type:Lab/Research institutions

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  • Palbociclib intermediate 571188-59-5

  • Casno:

    571188-59-5

    Palbociclib intermediate 571188-59-5

    Min.Order: 100 Gram

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  • CAS 571188-59-5 tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

  • Casno:

    571188-59-5

    CAS 571188-59-5 tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

    Min.Order: 1 Kilogram

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    1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

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  • Casno:

    571188-59-5

    Tert-butyl?4-(6-amino-3-pyridyl)piperazine-1-carboxylate

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    Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

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     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-85378921

    Address:Jintong international Building, No.113,Huayuangang Street, Gong shu District, Hangzhou,Zhejiang, China.

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  • PALBOCICLIB intermediates

  • Casno:

    571188-59-5

    PALBOCICLIB intermediates

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    We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to provide excellence in researching, manufacturing and drug discovery process. Our

    ACHIEVER SYSTEAM BIOCHEM CO., LTD. is one of the professional suppliers in Chinese pharmaceutical market and is specialized in custom synthesis, chemical/pharmaceutical/ pesticides

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    Business Type:Lab/Research institutions

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  • 4-(6-AMINOPYRIDIN-3-YL)PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

  • Casno:

    571188-59-5

    4-(6-AMINOPYRIDIN-3-YL)PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

    Min.Order: 1 Gram

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    Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

    AFINE CHEMICALS LIMITED is specialized in the fine chemicals and pharmaceuticals and we have enjoyed great popularity in world markets. Since 2005, we have been rapidly growing to

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     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-85134551

    Address:No. 206 Zhen Hua Road, Hangzhou 310030, Zhejiang, China

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  • 4-(6-Aminopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester Cas no. 571188-59-5 99.5%+

  • Casno:

    571188-59-5

    4-(6-Aminopyridin-3-yl)piperazine-1-carboxylic acid tert-butyl ester Cas no. 571188-59-5 99.5%+

    Min.Order: 1 Kilogram

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    100% owned factory, regulatory compliance and be audited. Shandong Shining Pharm：Provincial chemical industry park(the first batch of certified park in Shandong Province), raw material and intermediate production base. Bromination, high pressure, hig

    Shandong Shining Pharm, founded in 2013, is a high-tech enterprise Providing RSM and intermediates to both generic and innovation pharmacentical companies gollablly from research t

  •  Shangdong Shinning Pharm co.ltd

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:86-18912923751

    Address:Taishan Road, Ningyang Economic Development Zone, Tai'an, Shandong

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  • POB02

  • Casno:

    571188-59-5

    POB02

    Min.Order: 4 Kilogram

    FOB Price:  USD $ 0.0-0.0

    A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

    T&W GROUP was established in 2007, headquartered in Shanghai, China. By integrating people, technology and potential, we endeavor to work for a better life. We are in the business

  •  SHANGHAI T&W PHARMACEUTICAL CO., LTD.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-21-61551611

    Address:601, No. 1, 2277 Nong, Zu Chongzhi Road, Zhangjiang Hightech. Park, Pudong

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  • Tert-butyl 4-(6-amino-3-pyridyl)piperazine-1-carboxylate/High quality/Best price

  • Casno:

    571188-59-5

    Tert-butyl 4-(6-amino-3-pyridyl)piperazine-1-carboxylate/High quality/Best price

    Min.Order: 1 Gram

    FOB Price:  USD $ 1.0-1.0

    Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

    Shanghai Massive Chemical Technology Co., Ltd. is engaged in development, production and marketing Specialty Chemicals to satisfy the changing needs of the chemical industry. We sp

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     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86 21 34943721

    Address:Room 435, 4th floor, Building 9, No. 2568 Gudai Road,Minhang District, Shanghai,

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  • tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

  • Casno:

    571188-59-5

    tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

    Min.Order: 10 Gram

    FOB Price:  USD $ 100.0-100.0

    Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

    Hangyu Biotech is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and O

  •  Zibo Hangyu Biotechnology Development Co., Ltd

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-15965530500

    Address:Room1701, Tianxing Building,Licheng district, jinan, Shandong, China

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  • Lower Price Tert-Butyl 4-(6-Aminopyridin-3-yl)piperazine-1-carboxylate

  • Casno:

    571188-59-5

    Lower Price Tert-Butyl 4-(6-Aminopyridin-3-yl)piperazine-1-carboxylate

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0

    Product name: Tert-Butyl 4-(6-Aminopyridin-3-yl)piperazine-1-carboxylate CAS No.: 571188-59-5 Molecule Formula：C14H22N4O2 Molecule Weight：278.35 Purity: 98.0% Package: 25kg/drum Description：Light yellow to brown powder Manufacture Sta

    Siwei Development Group Ltd. is a reputed professional enterprise in China dedicated to the Amino Acids production and sales of fine chemical products.Over the years we have been m

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    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-571-82881840

    Address:Rm2-2-503 Zhongdingyuan, Xianghurenjia Wenyan Xiaoshan, Hangzhou China

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